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The last 5 uploaded publications
Picomolar Inhibitors of HIV Reverse Transcriptase Featuring Bicyclic Replacement of a Cyanovinylphenyl Group
Won-Gil Lee, Ricardo Gallardo‐Macias, Kathleen M. Frey, Krasimir A. Spasov, Mariela Bollini, Karen S. Anderson, William L. Jorgensen (2013). Picomolar Inhibitors of HIV Reverse Transcriptase Featuring Bicyclic Replacement of a Cyanovinylphenyl Group. Journal of the American Chemical Society, 135(44), pp. 16705-16713, DOI: 10.1021/ja408917n.
Article348 days agoPotent Inhibitors Active against HIV Reverse Transcriptase with K101P, a Mutation Conferring Rilpivirine Resistance
William T. Gray, Kathleen M. Frey, Sarah B. Laskey, Andrea C. Mislak, Krasimir A. Spasov, Won-Gil Lee, Mariela Bollini, Robert F. Siliciano, William L. Jorgensen, Karen S. Anderson (2015). Potent Inhibitors Active against HIV Reverse Transcriptase with K101P, a Mutation Conferring Rilpivirine Resistance. ACS Medicinal Chemistry Letters, 6(10), pp. 1075-1079, DOI: 10.1021/acsmedchemlett.5b00254.
Article348 days agoCrystal Structures of HIV-1 Reverse Transcriptase with Picomolar Inhibitors Reveal Key Interactions for Drug Design
Kathleen M. Frey, Mariela Bollini, Andrea C. Mislak, José A. Cisneros, Ricardo Gallardo‐Macias, William L. Jorgensen, Karen S. Anderson (2012). Crystal Structures of HIV-1 Reverse Transcriptase with Picomolar Inhibitors Reveal Key Interactions for Drug Design. Journal of the American Chemical Society, 134(48), pp. 19501-19503, DOI: 10.1021/ja3092642.
Article348 days agoStructure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants
Kathleen M. Frey, D.E. Puleo, Krasimir A. Spasov, Mariella Bollini, William L. Jorgensen, Karen S. Anderson (2015). Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants. Journal of Medicinal Chemistry, 58(6), pp. 2737-2745, DOI: 10.1021/jm501908a.
Article348 days agoPicomolar Inhibitors of HIV-1 Reverse Transcriptase: Design and Crystallography of Naphthyl Phenyl Ethers
Won‐Gil Lee, Kathleen M. Frey, Ricardo Gallardo‐Macias, Krasimir A. Spasov, Mariela Bollini, Karen S. Anderson, William L. Jorgensen (2014). Picomolar Inhibitors of HIV-1 Reverse Transcriptase: Design and Crystallography of Naphthyl Phenyl Ethers. ACS Medicinal Chemistry Letters, 5(11), pp. 1259-1262, DOI: 10.1021/ml5003713.
Article348 days ago