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The last 5 uploaded publications
NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease
Eilíse M. Ryan, Pranvera Sadiku, Patrícia Coelho, Emily Watts, Ailiang Zhang, Andrew J.M. Howden, Manuel A. Sánchez-García, Martin A. Bewley, Joby Cole, Brian J. McHugh, Wesley Vermaelen, Bart Ghesquière, Peter Carmeliet, Giovanny Rodriguez Blanco, Alex von Kriegsheim, Yolanda Sánchez, William L. Rumsey, James F. Callahan, George Cooper, Nick Parkinson, J. Kenneth Baillie, Doreen A. Cantrell, John McCafferty, Gourab Choudhury, Dave Singh, David H. Dockrell, Moira K. B. Whyte, Sarah R. Walmsley (2023). NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease. , 207(8), DOI: https://doi.org/10.1164/rccm.202203-0482oc.
Article78 days agoIL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses <i>In Vivo</i>
A.J. Harris, Ananda S. Mirchandani, Ruairi Lynch, Fiona Murphy, Liam Delaney, Donna M. Small, Patrícia Coelho, Emily Watts, Pranvera Sadiku, David Griffith, Rebecca Dickinson, Eilidh Clark, Joseph Willson, Tyler Morrison, Massimiliano Mazzone, Peter Carmeliet, Bart Ghesquière, Cecilia M. O’Kane, Daniel F. McAuley, Steve Jenkins, Moira K. B. Whyte, Sarah R. Walmsley (2019). IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses <i>In Vivo</i>. , 200(2), DOI: https://doi.org/10.1164/rccm.201808-1599oc.
Article78 days agoDifferential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function
Emily Watts, Joseph Willson, Simone Arienti, Pranvera Sadiku, Patrícia Coelho, Manuel A. Sánchez-García, Ailiang Zhang, Fiona Murphy, Rebecca Dickinson, Ananda S. Mirchandani, Tyler Morrison, Amy Lewis, Wesley Vermaelen, Bart Ghesquière, Peter Carmeliet, Massimiliano Mazzone, Patrick H. Maxwell, Christopher W. Pugh, David H. Dockrell, Moira K. B. Whyte, Sarah R. WalmsleyDifferential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function. , DOI: https://doi.org/10.6084/m9.figshare.24106686.
Dataset78 days agoDifferential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function
Emily Watts, Joseph Willson, Simone Arienti, Pranvera Sadiku, Patrícia Coelho, Manuel A. Sánchez-García, Ailiang Zhang, Fiona Murphy, Rebecca Dickinson, Ananda S. Mirchandani, Tyler Morrison, Amy Lewis, Wesley Vermaelen, Bart Ghesquière, Peter Carmeliet, Massimiliano Mazzone, Patrick H. Maxwell, Christopher W. Pugh, David H. Dockrell, Moira K. B. Whyte, Sarah R. WalmsleyDifferential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function. , DOI: https://doi.org/10.6084/m9.figshare.24106686.v2.
Dataset78 days agoNeutrophils fuel effective immune responses through gluconeogenesis and glycogenesis
Pranvera Sadiku, Joseph Willson, Eilíse M. Ryan, David Sammut, Patrícia Coelho, Emily Watts, Robert Grecian, Jason M. Young, Martin A. Bewley, Simone Arienti, Ananda S. Mirchandani, Manuel A. Sánchez-García, Tyler Morrison, Ailing Zhang, Leila Reyes, Tobias Griessler, Privjyot Jheeta, Gordon Paterson, Christopher J Graham, John P. Thomson, J. Kenneth Baillie, A.A. Roger Thompson, Jessie-May Morgan, Abel Acosta‐Sanchez, Verónica M. Dardé, Jordi Durán, Joan J. Guinovart, Giovanny Rodriguez Blanco, Alex von Kriegsheim, Richard R. Meehan, Massimiliano Mazzone, David H. Dockrell, Bart Ghesquière, Peter Carmeliet, Moira K. B. Whyte, Sarah R. Walmsley (2021). Neutrophils fuel effective immune responses through gluconeogenesis and glycogenesis. , 33 (5), DOI: https://doi.org/10.1016/j.cmet.2021.03.018.
Corrigendum78 days ago