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The last 5 uploaded publications
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect
Ester Lara, Antonello Mai, Vincenzo Calvanese, Lucia Altucci, Pilar López‐Nieva, María Luz Martínez‐Chantar, Marta Varela‐Rey, Dante Rotili, Angela Nebbioso, Santiago Ropero, Guillermo Montoya, Julen Oyarzábal, Sheyla Velasco, Manuel Serrano, M Witt, Ana Villar‐Garea, A Inhof, José M. Mato, Manel Esteller, Mario F. Fraga (2008). Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect. , 28(6), DOI: https://doi.org/10.1038/onc.2008.436.
Article188 days agoEpigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells
Jesús Espada, Esteban Ballestar, Raffaella Santoro, Mario F. Fraga, Ana Villar‐Garea, Attila Németh, L. Lopez-Serra, Santiago Ropero, Agustı́n Aranda, Helena Orozco, Vanessa Moreno, Ángeles Juarranz, J. C. Stockert, Gernot Längst, Ingrid Grummt, Wendy A. Bickmore, Manel Esteller (2007). Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells. , 35(7), DOI: https://doi.org/10.1093/nar/gkm118.
Article188 days agoLoss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
Mario F. Fraga, Esteban Ballestar, Ana Villar‐Garea, Manuel Boix-Chornet, Jesús Espada, Gunnar Schotta, Tiziana Bonaldi, Claire E. Haydon, Santiago Ropero, Kevin Petrie, N. Gopalakrishna Iyer, Alberto Pérez‐Rosado, Enrique Calvo, Juan Antonio López, Amparo Cano, Marı́a José Calasanz, Dolors Colomer, Miguel Á. Piris, Natalie G. Ahn, Axel Imhof, Carlos Caldas, Thomas Jenuwein, Manel Esteller (2005). Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. , 37(4), DOI: https://doi.org/10.1038/ng1531.
Article188 days agoDNA Demethylating Agents and Chromatin-Remodelling Drugs: Which, How and Why?
Ana Villar‐Garea, Manel Esteller (2003). DNA Demethylating Agents and Chromatin-Remodelling Drugs: Which, How and Why?. , 4(1), DOI: https://doi.org/10.2174/1389200033336757.
Article188 days agoProcaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells.
Ana Villar‐Garea, Mario F. Fraga, Jesús Espada, Manel Esteller (2003). Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells.. , 63(16)
Article188 days ago