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The last 5 uploaded publications
Kiwa is a membrane-embedded defense supercomplex activated at phage attachment sites
Zhiying Zhang, Thomas C. Todeschini, Yi Wu, Roman Kogay, Ali Naji, José Manuel Jiménez Rodríguez, Rupavidhya Mondi, Daniel Kaganovich, David W. Taylor, Jack P. K. Bravo, Marianna Teplova, Triana Amen, Eugene V Koonin, Dinshaw J. Patel, Franklin L Nobrega (2025). Kiwa is a membrane-embedded defense supercomplex activated at phage attachment sites. , 188(21), DOI: https://doi.org/10.1016/j.cell.2025.07.002.
Article95 days agoYprA family helicases provide the missing link between diverse prokaryotic immune systems
Ryan T. Bell, Thomas Gaudin, Yi Wu, Sofya K. Garushyants, Harutyun Sahakyan, Kira S. Makarova, Yuri I. Wolf, Simon A. Jackson, Franklin L Nobrega, Chase L. Beisel, Eugene V Koonin (2025). YprA family helicases provide the missing link between diverse prokaryotic immune systems. , DOI: https://doi.org/10.1101/2025.09.15.676423.
Preprint95 days agoBacterial defense systems exhibit synergistic anti-phage activity
Yi Wu, Sofya K. Garushyants, Anne van den Hurk, Cristian Aparicio-Maldonado, Simran Krishnakant Kushwaha, Claire King, Yaqing Ou, Thomas C. Todeschini, Martha R. J. Clokie, Andrew Millard, Yilmaz Emre Gençay, Eugene V Koonin, Franklin L Nobrega (2024). Bacterial defense systems exhibit synergistic anti-phage activity. , 32(4), DOI: https://doi.org/10.1016/j.chom.2024.01.015.
Article95 days agoKiwa is a bacterial membrane-embedded defence supercomplex activated by phage-induced membrane changes
Zhiying Zhang, Thomas C. Todeschini, Yi Wu, Roman Kogay, Ali Naji, José Manuel Jiménez Rodríguez, Rupavidhya Mondi, Daniel Kaganovich, David W. Taylor, Jack P. K. Bravo, Marianna Teplova, Triana Amen, Eugene V Koonin, Dinshaw J. Patel, Franklin L Nobrega (2023). Kiwa is a bacterial membrane-embedded defence supercomplex activated by phage-induced membrane changes. , DOI: https://doi.org/10.1101/2023.02.26.530102.
Preprint95 days agoSynergistic anti-phage activity of bacterial defence systems
Yi Wu, Sofya K. Garushyants, Anne van den Hurk, Cristian Aparicio-Maldonado, Simran Krishnakant Kushwaha, Claire King, Yaqing Ou, Thomas C. Todeschini, Martha R. J. Clokie, Andrew Millard, Yilmaz Emre Gençay, Eugene V Koonin, Franklin L Nobrega (2022). Synergistic anti-phage activity of bacterial defence systems. , DOI: https://doi.org/10.1101/2022.08.21.504612.
Preprint95 days ago