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The last 5 uploaded publications
Novel indolylarylsulfone derivatives as covalent HIV-1 reverse transcriptase inhibitors specifically targeting the drug-resistant mutant Y181C
Ping Gao, Shu Song, Estrella Frutos-Beltrán, Wenxin Li, Bin Sun, Dongwei Kang, Jinmi Zou, Jian Zhang, Christophe Pannecouque, De Clercq Erik, Luis Menéndez‐Arias, Peng Zhan, Xinyong Liu (2020). Novel indolylarylsulfone derivatives as covalent HIV-1 reverse transcriptase inhibitors specifically targeting the drug-resistant mutant Y181C. , 30, DOI: https://doi.org/10.1016/j.bmc.2020.115927.
Article44 days agoDiscovery of small molecular inhibitors targeting HIV-1 gp120–CD4 interaction drived from BMS-378806
Tao Liu, Boshi Huang, Peng Zhan, De Clercq Erik, Xinyong Liu (2014). Discovery of small molecular inhibitors targeting HIV-1 gp120–CD4 interaction drived from BMS-378806. , 86, DOI: https://doi.org/10.1016/j.ejmech.2014.09.012.
Article44 days agoDesign, Synthesis and Biological Evaluation of Substituted Guanidine Indole Derivatives as Potential Inhibitors of HIV-1 Tat-TAR Interaction
Jun Wang, Yan Wang, Zhenyu Li, Peng Zhan, Ru-Jun Bai, Christophe Pannecouque, Jan Balzarini, De Clercq Erik, Xinyong Liu (2013). Design, Synthesis and Biological Evaluation of Substituted Guanidine Indole Derivatives as Potential Inhibitors of HIV-1 Tat-TAR Interaction. , 10(7), DOI: https://doi.org/10.2174/1573406410666140306151815.
Article44 days agoSynthesis, In Vitro and In Vivo Release Kinetics, and Anti‐HIV Activity of A Sustained‐Release Prodrug (mPEG‐AZT) of 3′‐Azido‐3′‐deoxythymidine (AZT, Zidovudine)
Wenjun Li, Yu Chang, Peng Zhan, Na Zhang, Xinyong Liu, Christophe Pannecouque, De Clercq Erik (2010). Synthesis, In Vitro and In Vivo Release Kinetics, and Anti‐HIV Activity of A Sustained‐Release Prodrug (mPEG‐AZT) of 3′‐Azido‐3′‐deoxythymidine (AZT, Zidovudine). , 5(11), DOI: https://doi.org/10.1002/cmdc.201000352.
Article44 days agoChemInform Abstract: Synthesis and anti‐HIV Activity Evaluation of 2‐(4‐(Naphthalen‐2‐yl)‐1,2,3‐thiadiazol‐5‐ylthio)‐N‐acetamides as Novel Non‐Nucleoside HIV‐1 Reverse Transcriptase Inhibitors.
Peng Zhan, Xinyong Liu, Zengjun Fang, Zhenyu Li, Christophe Pannecouque, De Clercq Erik (2010). ChemInform Abstract: Synthesis and anti‐HIV Activity Evaluation of 2‐(4‐(Naphthalen‐2‐yl)‐1,2,3‐thiadiazol‐5‐ylthio)‐N‐acetamides as Novel Non‐Nucleoside HIV‐1 Reverse Transcriptase Inhibitors.. , 41(9), DOI: https://doi.org/10.1002/chin.201009136.
Article44 days ago