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The last 5 uploaded publications
Discovery of a Potent, Selective, and Efficacious Class of Reversible α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Effective as Analgesics
Dale L. Boger, Hiroshi Miyauchi, Wu Du, Christophe Hardouin, Robert Fecik, Heng Cheng, Inkyu Hwang, Michael P. Hedrick, Donmienne Leung, Orlando Acevedo, Cristiano R. W. Guimarães, William L. Jorgensen, Benjamin F. Cravatt (2004). Discovery of a Potent, Selective, and Efficacious Class of Reversible α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Effective as Analgesics. Journal of Medicinal Chemistry, 48(6), pp. 1849-1856, DOI: 10.1021/jm049614v.
Article364 days agoElucidation of Fatty Acid Amide Hydrolase Inhibition by Potent α-Ketoheterocycle Derivatives from Monte Carlo Simulations
Cristiano R. W. Guimarães, Dale L. Boger, William L. Jorgensen (2005). Elucidation of Fatty Acid Amide Hydrolase Inhibition by Potent α-Ketoheterocycle Derivatives from Monte Carlo Simulations. Journal of the American Chemical Society, 127(49), pp. 17377-17384, DOI: 10.1021/ja055438j.
Article364 days agoSynthesis and Evaluation of Selected Key Methyl Ether Derivatives of Vancomycin Aglycon
Christine M. Crane, Joshua G. Pierce, Siegfried S. F. Leung, Julian Tirado‐Rives, William L. Jorgensen, Dale L. Boger (2010). Synthesis and Evaluation of Selected Key Methyl Ether Derivatives of Vancomycin Aglycon. Journal of Medicinal Chemistry, 53(19), pp. 7229-7235, DOI: 10.1021/jm100946e.
Article364 days agoEnergetic Preferences for α,β versus β,γ Unsaturation
Patrick S. Lee, Wu Du, Dale L. Boger, William L. Jorgensen (2004). Energetic Preferences for α,β versus β,γ Unsaturation. The Journal of Organic Chemistry, 69(16), pp. 5448-5453, DOI: 10.1021/jo049363y.
Article364 days ago