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The last 5 uploaded publications
IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses <i>In Vivo</i>
A.J. Harris, Ananda S. Mirchandani, Ruairi Lynch, Fiona Murphy, Liam Delaney, Donna M. Small, Patrícia Coelho, Emily Watts, Pranvera Sadiku, David Griffith, Rebecca Dickinson, Eilidh Clark, Joseph Willson, Tyler Morrison, Massimiliano Mazzone, Peter Carmeliet, Bart Ghesquière, Cecilia M. O’Kane, Daniel F. McAuley, Steve Jenkins, Moira K. B. Whyte, Sarah R. Walmsley (2019). IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses <i>In Vivo</i>. , 200(2), DOI: https://doi.org/10.1164/rccm.201808-1599oc.
Article78 days agoDifferential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function
Emily Watts, Joseph Willson, Simone Arienti, Pranvera Sadiku, Patrícia Coelho, Manuel A. Sánchez-García, Ailiang Zhang, Fiona Murphy, Rebecca Dickinson, Ananda S. Mirchandani, Tyler Morrison, Amy Lewis, Wesley Vermaelen, Bart Ghesquière, Peter Carmeliet, Massimiliano Mazzone, Patrick H. Maxwell, Christopher W. Pugh, David H. Dockrell, Moira K. B. Whyte, Sarah R. WalmsleyDifferential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function. , DOI: https://doi.org/10.6084/m9.figshare.24106686.
Dataset78 days agoProlyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses
Pranvera Sadiku, Joseph Willson, Rebecca Dickinson, Fiona Murphy, A.J. Harris, Amy Lewis, David Sammut, Ananda S. Mirchandani, Eilíse M. Ryan, Emily Watts, A. A. Roger Thompson, Helen M. Marriott, David H. Dockrell, Cormac T. Taylor, Martin Schneider, Patrick H. Maxwell, Edwin R. Chilvers, Massimiliano Mazzone, Verónica M. Dardé, Christopher W. Pugh, Peter J. Ratcliffe, Christopher J. Schofield, Bart Ghesquière, Peter Carmeliet, Moira K. B. Whyte, Sarah R. Walmsley (2017). Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses. , 127(9), DOI: https://doi.org/10.1172/jci90848.
Article78 days agoDifferential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function
Emily Watts, Joseph Willson, Simone Arienti, Pranvera Sadiku, Patrícia Coelho, Manuel A. Sánchez-García, Ailiang Zhang, Fiona Murphy, Rebecca Dickinson, Ananda S. Mirchandani, Tyler Morrison, Amy Lewis, Wesley Vermaelen, Bart Ghesquière, Peter Carmeliet, Massimiliano Mazzone, Patrick H. Maxwell, Christopher W. Pugh, David H. Dockrell, Moira K. B. Whyte, Sarah R. WalmsleyDifferential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function. , DOI: https://doi.org/10.6084/m9.figshare.24106686.v2.
Dataset78 days agoHypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism
A. A. Roger Thompson, Rebecca Dickinson, Fiona Murphy, John P. Thomson, Helen M. Marriott, Adriana Tavares, Joseph Willson, Lynne Williams, Amy Lewis, Ananda S. Mirchandani, Patricia Dos Santos Coelho, Catherine Doherty, Eilíse M. Ryan, Emily Watts, Nicholas M. Morton, Shareen Forbes, Roland H. Stimson, Abdul Hameed, Nadine Arnold, Julie A. Preston, Allan Lawrie, Veronica Finisguerra, Massimiliano Mazzone, Pranvera Sadiku, Jermaine Goveia, Federico Taverna, Peter Carmeliet, Simon J. Foster, Edwin R. Chilvers, Andrew S. Cowburn, David H. Dockrell, Randall S. Johnson, Richard R. Meehan, Moira K. B. Whyte, Sarah R. Walmsley (2017). Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism. , 2(8), DOI: https://doi.org/10.1126/sciimmunol.aal2861.
Article78 days ago