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The last 5 uploaded publications
Human colon stem cells are the principal epithelial responders to bacterial antigens
Maaike Hillegonda de Vries, Claartje Meddens, Hemme Hijma, Anne‐Claire Berrens, Suze A. Jansen, Berend A. P. Kooiman, Scott B Snapper, Hans Clevers, Michal Mokrý, Ewart Kuijk, Edward E. S. Nieuwenhuis (2025). Human colon stem cells are the principal epithelial responders to bacterial antigens. , DOI: https://doi.org/10.1101/2025.02.07.637053.
Preprint163 days agoA collection of patient-derived intestinal organoid lines reveals epithelial pheno-types associated with genetic drivers of pediatric inflammatory bowel disease
Zahra Shojaei Jeshvaghani, Carmen Argmann, Michal Mokrý, Johan H. van Es, Maaike Hillegonda de Vries, Lauren V Collen, Daniel Kotlarz, Mia Sveen, Phillip Comella, Scott B Snapper, Christoph Klein, Eric E. Schadt, Hans Clevers, Ewart Kuijk, Edward E. S. Nieuwenhuis (2025). A collection of patient-derived intestinal organoid lines reveals epithelial pheno-types associated with genetic drivers of pediatric inflammatory bowel disease. , DOI: https://doi.org/10.1101/2025.06.11.659052.
Preprint163 days agoBipotent Liver Progenitors Depend on Glycolysis and Mitochondrial Pyruvate Oxidation for Stem Cell Functions
Imre F. Schene, Rúben J. Ramos, Anke H.M. van Vugt, Hoa Truong, D.J. van den Heuvel, Hans C. Gerritsen, Riekelt H. Houtkooper, Michel van Weeghel, Sabine Middendorp, Michal Mokrý, Bart Spee, Kerstin Schneeberger, Peter G. J. Nikkels, Meritxell Huch, Hans Clevers, Edward E. S. Nieuwenhuis, Peter M. van Hasselt, Sabine A. Fuchs (2020). Bipotent Liver Progenitors Depend on Glycolysis and Mitochondrial Pyruvate Oxidation for Stem Cell Functions. , DOI: https://doi.org/10.2139/ssrn.3564994.
Article144 days agoStem Cells are the Principal Intestinal Epithelial Responders to Bacterial Antigens
Claartje Meddens, Maaike Hillegonda de Vries, Hemme Hijma, Anne Claire Berrens, Bart Westendorp, Jet van der Spek, Berend A. P. Kooiman, Renée Schreurs, Erik Lijster, Sinisa Prelic, Ninke M. Nieuwenhuis, Marjolein Mijnders, Miguel A. Vega, Suze A. Jansen, Evelyn S. Hanemaaijer, Nico Lansu, Noortje A. M. van den Dungen, Madeleine J. Bunders, Sabine Middendorp, Hans Clevers, Michal Mokrý, Edward E. S. Nieuwenhuis (2019). Stem Cells are the Principal Intestinal Epithelial Responders to Bacterial Antigens. , DOI: https://doi.org/10.2139/ssrn.3485163.
Article144 days agoVery Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies
Jodie Ouahed, Elizabeth A. Spencer, Daniel Kotlarz, Dror S. Shouval, Matthew Kowalik, Kaiyue Peng, Michael Field, Leslie Grushkin-Lerner, Sung‐Yun Pai, Athos Bousvaros, Judy H. Cho, Carmen Argmann, Eric E. Schadt, Dermot McGovern, Michal Mokrý, Edward E. S. Nieuwenhuis, Hans Clevers, Fiona Powrie, Holm H. Uhlig, Christoph Klein, Aleixo M. Muise, Marla C. Dubinsky, Scott B Snapper (2019). Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies. , 26(6), DOI: https://doi.org/10.1093/ibd/izz259.
Article144 days ago