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The last 5 uploaded publications
NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1
Sinéad M. Miggin, Eva M. Pålsson‐McDermott, Aisling Dunne, Caroline A. Jefferies, Emmanuel Pinteaux, Kathy Banahan, Caroline Murphy, Paul N. Moynagh, Masahiro Yamamoto, Akira Shizuo, Nancy J. Rothwell, Douglas T. Golenbock, Katherine A. Fitzgerald, Luke O'neill (2007). NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1. Proceedings of the National Academy of Sciences, 104(9), pp. 3372-3377, DOI: 10.1073/pnas.0608100104.
Article255 days ago100 NF-κB Activation by Mal/Tirap is Regulated by Caspase-1
Sinéad M. Miggin, Eva M. Pålsson‐McDermott, Aisling Dunne, Caroline A. Jefferies, Emmanuel Pinteaux, Kathy Banahan, Caroline Murphy, Paul N. Moynagh, Masahiro Yamamoto, Akira Shizuo, Nancy J. Rothwell, Douglas T. Golenbock, Katherine A. Fitzgerald, Luke O'neill (2007). 100 NF-κB Activation by Mal/Tirap is Regulated by Caspase-1. Cytokine, 39(1), pp. 27-28, DOI: 10.1016/j.cyto.2007.07.105.
Article249 days agoMal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
Katherine A. Fitzgerald, Eva M. Pålsson‐McDermott, Andrew Bowie, Caroline A. Jefferies, Ashley Mansell, Gareth Brady, Elizabeth Brint, Aisling Dunne, Pearl Gray, Mary T. Harte, Diane McMurray, Dirk E. Smith, John E. Sims, Timothy A. Bird, Luke O'neill (2001). Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature, 413(6851), pp. 78-83, DOI: 10.1038/35092578.
Article249 days agoActivation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
Seth L. Masters, Aisling Dunne, Shoba Subramanian, Rebecca L. Hull, Gillian M. Tannahill, Fiona A. Sharp, Christine Becker, Luigi Franchi, Eiji Yoshihara, Zhe Chen, N Mullooly, Lisa A. Mielke, James Harris, Rebecca C. Coll, Kingston H. G. Mills, K. Hun Mok, Philip Newsholme, Gabriel Nuñez, Junji Yodoi, Steven E. Kahn, Ed C. Lavelle, Luke O'neill (2010). Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes. Nature Immunology, 11(10), pp. 897-904, DOI: 10.1038/ni.1935.
Article249 days agoThe Interleukin-1 Receptor/Toll-Like Receptor Superfamily: Signal Transduction During Inflammation and Host Defense
Aisling Dunne, Luke O'neill (2003). The Interleukin-1 Receptor/Toll-Like Receptor Superfamily: Signal Transduction During Inflammation and Host Defense. Science s STKE, 2003(171), DOI: 10.1126/stke.2003.171.re3.
Article249 days ago