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The last 5 uploaded publications
Role for NLRP3 Inflammasome–mediated, IL-1β–Dependent Responses in Severe, Steroid-Resistant Asthma
Richard Kim, James Pinkerton, Ama‐Tawiah Essilfie, Avril A. B. Robertson, Katherine J. Baines, Alexandra C. Brown, Jemma Mayall, Md Khadem Ali, Malcolm R. Starkey, Nicole G. Hansbro, Jeremy A. Hirota, Lisa G. Wood, Jodie L. Simpson, Darryl A. Knight, Peter Wark, Peter G. Gibson, Luke O'neill, Matthew A. Cooper, Jay C. Horvat, Philip M. Hansbro (2017). Role for NLRP3 Inflammasome–mediated, IL-1β–Dependent Responses in Severe, Steroid-Resistant Asthma. American Journal of Respiratory and Critical Care Medicine, 196(3), pp. 283-297, DOI: 10.1164/rccm.201609-1830oc.
Article250 days agoItaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
Marah C. Runtsch, Stefano Angiari, Alexander Hooftman, Ridhima Wadhwa, Yanling Zhang, Yunan Zheng, Joseph S. Spina, Melanie C. Ruzek, M.A. Argiriadi, Anne F. McGettrick, Rui Santalla Méndez, Alessia Zotta, Christian G. Peace, Aoife Walsh, Roberta Chirillo, Emily Hams, Padraic G. Fallon, Ranjith Jayaraman, Kamal Dua, Alexandra C. Brown, Richard Kim, Jay C. Horvat, Philip M. Hansbro, Chu Wang, Luke O'neill (2022). Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages. Cell Metabolism, 34(3), pp. 487-501.e8, DOI: 10.1016/j.cmet.2022.02.002.
Article250 days agoInflammasomes in the lung
James Pinkerton, Richard Kim, Avril A. B. Robertson, Jeremy A. Hirota, Lisa G. Wood, Darryl A. Knight, Matthew A. Cooper, Luke O'neill, Jay C. Horvat, Philip M. Hansbro (2017). Inflammasomes in the lung. Molecular Immunology, 86, pp. 44-55, DOI: 10.1016/j.molimm.2017.01.014.
Article250 days agoRelationship between type 2 cytokine and inflammasome responses in obesity-associated asthma
James Pinkerton, Richard Kim, Alexandra C. Brown, Brittany Rae, Chantal Donovan, Jemma Mayall, Olivia R. Carroll, Md Khadem Ali, Hayley A. Scott, Bronwyn S. Berthon, Katherine J. Baines, Malcolm R. Starkey, Nazanin Zounemat Kermani, Yike Guo, Avril A. B. Robertson, Luke O'neill, Ian M. Adcock, Matthew A. Cooper, Peter G. Gibson, Lisa G. Wood, Philip M. Hansbro, Jay C. Horvat (2021). Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma. Journal of Allergy and Clinical Immunology, 149(4), pp. 1270-1280, DOI: 10.1016/j.jaci.2021.10.003.
Article250 days agoCharacterization and inhibition of inflammasome responses in severe and non-severe asthma
Jay C. Horvat, Richard Kim, Natasha Weaver, Christopher Augood, Alexandra C. Brown, Chantal Donovan, Pierrick Dupré, Lakshitha P Gunawardhana, Jemma Mayall, Nicole G. Hansbro, Avril A. B. Robertson, Luke O'neill, Matthew A. Cooper, Elizabeth Holliday, Philip M. Hansbro, Peter G. Gibson (2023). Characterization and inhibition of inflammasome responses in severe and non-severe asthma. Respiratory Research, 24(1), DOI: 10.1186/s12931-023-02603-2.
Article250 days ago