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The last 5 uploaded publications
Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp3 values and favorable drug-like properties
Xiangyi Jiang, Boshi Huang, Fisayo A. Olotu, Jing Li, Dongwei Kang, Zhao Wang, De Clercq Erik, Mahmoud E. S. Soliman, Christophe Pannecouque, Xinyong Liu, Peng Zhan (2020). Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp3 values and favorable drug-like properties. , 213, DOI: https://doi.org/10.1016/j.ejmech.2020.113051.
Article36 days agoDesign, synthesis, and evaluation of “dual-site”-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase
Da Feng, Xiaofang Zuo, Lanlan Jing, Chin‐Ho Chen, Fisayo A. Olotu, Hao Lin, Mahmoud E. S. Soliman, De Clercq Erik, Christophe Pannecouque, Kuo‐Hsiung Lee, Dongwei Kang, Xinyong Liu, Peng Zhan (2020). Design, synthesis, and evaluation of “dual-site”-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase. , 211, DOI: https://doi.org/10.1016/j.ejmech.2020.113063.
Article36 days ago