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The last 5 uploaded publications
216eP MegaMOST - A multicenter, open-label, molecularly selected bayesian phase II platform trial in advanced or metastatic solid tumors: Final analysis of the trametinib cohort
Olivier Trédan, E.B. Saada, Cécile Dalban, Sophie Cousin, A. Le Cesne, A. Italiano, François Bertucci, C.A. Gomez-Roca, Lauriane Eberst, I. L. Ray-Coquard, Loïc Verlingue, P. Cassier, Valéry Attignon, Sylvie Chabaud, Romaine Mayet, E. Cauquil, G. Garin, David Pérol, Jean Yves Blay (2025). 216eP MegaMOST - A multicenter, open-label, molecularly selected bayesian phase II platform trial in advanced or metastatic solid tumors: Final analysis of the trametinib cohort. , 36, DOI: https://doi.org/10.1016/j.annonc.2025.08.648.
Article23 days agoReply to: Critical evaluation of the ProfiLER-02 study design and outcomes
Olivier Trédan, Marie-Sarah Cabrillac, Sylvie Chabaud, Gwenaëlle Garin, David Pérol, Jean Yves Blay (2025). Reply to: Critical evaluation of the ProfiLER-02 study design and outcomes. , 31(10), DOI: https://doi.org/10.1038/s41591-025-03960-9.
Letter23 days ago241eP Whole genome and RNA sequencing for the selection of targeted therapy in advanced cancer patients
Ouissam Al Jarroudi, S. Boyault, Camille Léonce, Anthony Ferrari, A. Buisson, I. Ray-Coquard, T. Bachelot, Mehdi Brahmi, A. Dufresne, Clélia Coutzac, Anne Mc Leer, S. Lantuejoul, Christine Vinciguerra, Louis Larrouquère, Alain Bonneville, Nadège Corradini, Pierre Leblond, Olivier Trédan, Jean Yves Blay, Pierre Saintigny (2025). 241eP Whole genome and RNA sequencing for the selection of targeted therapy in advanced cancer patients. , 36, DOI: https://doi.org/10.1016/j.annonc.2025.08.671.
Article23 days agoBroad versus limited gene panels to guide treatment in patients with advanced solid tumors: a randomized controlled trial
Olivier Trédan, Damien Pouessel, Nicolas Penel, Sylvie Chabaud, Carlos Gomez‐Roca, Jean-Pierre Delord, Diane Pannier, Mehdi Brahmi, Michel Fabbro, Marie-Eve Garcia, Delphine Larrieu‐Ciron, Isabelle Ray‐Coquard, Marie Viala, Antoîne Italiano, Diégo Tosi, Philippe A. Cassier, Armelle Dufresne, Valéry Attignon, Sandrine Boyault, Isabelle Treilleux, Alain Viari, David Pérol, Jean Yves Blay (2025). Broad versus limited gene panels to guide treatment in patients with advanced solid tumors: a randomized controlled trial. , 31(5), DOI: https://doi.org/10.1038/s41591-025-03613-x.
Article23 days agoAbstract 6360: A tumor agnostic composite gene expression signature identifies three groups of patients treated with immune checkpoint blockade with distinct clinical outcome
Mehdi Lamkhioued, Guillaume Robert-Siegwald, Roxane M. Pommier, David M. Tricoli, Camille Brodin, Valéry Attignon, Nicolas Gadot, Séverine Tabone‐Eglinger, F.N. Jerome, Aurélie Swalduz, Isabelle Ray‐Coquard, Eve‐Marie Neidhardt, Clélia Coutzac, Loïc Verlingue, Olivier Trédan, Jean Yves Blay, Christophe Caux, Alain Viari, Nicolas Poirier, Aurore Morello, Isabelle Girault, Pierre Saintigny (2025). Abstract 6360: A tumor agnostic composite gene expression signature identifies three groups of patients treated with immune checkpoint blockade with distinct clinical outcome. , 85(8_Supplement_1), DOI: https://doi.org/10.1158/1538-7445.am2025-6360.
Article23 days ago