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The last 5 uploaded publications
NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1
Sinéad M. Miggin, Eva M. Pålsson‐McDermott, Aisling Dunne, Caroline A. Jefferies, Emmanuel Pinteaux, Kathy Banahan, Caroline Murphy, Paul N. Moynagh, Masahiro Yamamoto, Akira Shizuo, Nancy J. Rothwell, Douglas T. Golenbock, Katherine A. Fitzgerald, Luke O'neill (2007). NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1. Proceedings of the National Academy of Sciences, 104(9), pp. 3372-3377, DOI: 10.1073/pnas.0608100104.
Article253 days ago100 NF-κB Activation by Mal/Tirap is Regulated by Caspase-1
Sinéad M. Miggin, Eva M. Pålsson‐McDermott, Aisling Dunne, Caroline A. Jefferies, Emmanuel Pinteaux, Kathy Banahan, Caroline Murphy, Paul N. Moynagh, Masahiro Yamamoto, Akira Shizuo, Nancy J. Rothwell, Douglas T. Golenbock, Katherine A. Fitzgerald, Luke O'neill (2007). 100 NF-κB Activation by Mal/Tirap is Regulated by Caspase-1. Cytokine, 39(1), pp. 27-28, DOI: 10.1016/j.cyto.2007.07.105.
Article247 days agoSuccinate is an inflammatory signal that induces IL-1β through HIF-1α
Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik, Eva M. Pålsson‐McDermott, Anne F. McGettrick, Gautam Goel, Christian Frezza, Nicholas J. Bernard, Beth Kelly, Niamh H. Foley, Liang Zheng, Agnès Gardet, Zhen Tong, S. S. Jany, Sinéad C. Corr, Moritz Haneklaus, Brian E. Caffrey, Kerry A. Pierce, Sarah R. Walmsley, Federico C. Beasley, Eoin P. Cummins, Victor Nizet, Moira K. B. Whyte, Cormac T. Taylor, Hening Lin, Seth L. Masters, Eyal Gottlieb, Vincent P. Kelly, Clary B. Clish, Philip E. Auron, Ramnik J. Xavier, Luke O'neill (2013). Succinate is an inflammatory signal that induces IL-1β through HIF-1α. Nature, 496(7444), pp. 238-242, DOI: 10.1038/nature11986.
Article247 days agoMal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
Katherine A. Fitzgerald, Eva M. Pålsson‐McDermott, Andrew Bowie, Caroline A. Jefferies, Ashley Mansell, Gareth Brady, Elizabeth Brint, Aisling Dunne, Pearl Gray, Mary T. Harte, Diane McMurray, Dirk E. Smith, John E. Sims, Timothy A. Bird, Luke O'neill (2001). Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature, 413(6851), pp. 78-83, DOI: 10.1038/35092578.
Article247 days agoSignal transduction by the lipopolysaccharide receptor, Toll‐like receptor‐4
Eva M. Pålsson‐McDermott, Luke O'neill (2004). Signal transduction by the lipopolysaccharide receptor, Toll‐like receptor‐4. Immunology, 113(2), pp. 153-162, DOI: 10.1111/j.1365-2567.2004.01976.x.
Article247 days ago