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The last 5 uploaded publications
Synthesis and evaluation of the biological activity of N′-[2-oxo-1,2 dihydro-3H-indol-3-ylidene] benzohydrazides as potential anticancer agents
Arpit Katiyar, Mahesh Hegde, Sujeet Kumar, Vidya Gopalakrishnan, Khyati Bhatelia, Kavya Ananthaswamy, Sureshbabu A. Ramareddy, De Clercq Erik, Bibha Choudhary, Dominique Schols, Sathees C. Raghavan, Subhas S. Karki (2015). Synthesis and evaluation of the biological activity of N′-[2-oxo-1,2 dihydro-3H-indol-3-ylidene] benzohydrazides as potential anticancer agents. , 5(56), DOI: https://doi.org/10.1039/c5ra01528f.
Article45 days ago2-(4-Chlorobenzyl)-6-arylimidazo[2,1-b][1,3,4]thiadiazoles: Synthesis, cytotoxic activity and mechanism of action
Sujeet Kumar, Mahesh Hegde, Vidya Gopalakrishnan, Vinaya Kumar Renuka, Sureshbabu A. Ramareddy, De Clercq Erik, Dominique Schols, Anil Kumar Gudibabande Narasimhamurthy, Sathees C. Raghavan, Subhas S. Karki (2014). 2-(4-Chlorobenzyl)-6-arylimidazo[2,1-b][1,3,4]thiadiazoles: Synthesis, cytotoxic activity and mechanism of action. , 84, DOI: https://doi.org/10.1016/j.ejmech.2014.07.054.
Article45 days agoSynthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication
Renato T. Skerlj, Gary Bridger, Ernest J. McEachern, Curtis Harwig, Christopher R. Smith, Trevor Wilson, D. R. VEALE, Helen S. Yee, Jason Crawford, Krystyna A. Skupinska, Rossana Wauthy, Wen Yang, Yongbao Zhu, David Bogucki, Maria Di Fluri, Jonathon Langille, Dana Huskens, De Clercq Erik, Dominique Schols (2010). Synthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication. , 21(1), DOI: https://doi.org/10.1016/j.bmcl.2010.11.023.
Article45 days agoPronounced in vitro and in vivo antiretroviral activity of 5-substituted 2,4-diamino-6-[2-(phosphonomethoxy)ethoxy] pyrimidines
Jan Balzarini, Dominique Schols, Kristel Van Laethem, De Clercq Erik, Dana Hocková, Milena Masojı́dková, Antonı́n Holý (2006). Pronounced in vitro and in vivo antiretroviral activity of 5-substituted 2,4-diamino-6-[2-(phosphonomethoxy)ethoxy] pyrimidines. , 59(1), DOI: https://doi.org/10.1093/jac/dkl454.
Article45 days agoThe candidate microbicide CADA, an entry inhibitor that specifically targets the cellular CD4 receptor, prevents HIV and SIV infection of human and simian cells
Kurt Vermeire, Thomas W. Bell, S. Anugu, N.H. Duffy, Roger Le Grand, De Clercq Erik, Dominique Schols (2006). The candidate microbicide CADA, an entry inhibitor that specifically targets the cellular CD4 receptor, prevents HIV and SIV infection of human and simian cells. , 70(1)
Article45 days ago