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The last 5 uploaded publications
Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography
Albert H. Chan, Won‐Gil Lee, Krasimir A. Spasov, José A. Cisneros, Shalley N. Kudalkar, Zaritza O. Petrova, Amanda B. Buckingham, Karen S. Anderson, William L. Jorgensen (2017). Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography. Proceedings of the National Academy of Sciences, 114(36), pp. 9725-9730, DOI: 10.1073/pnas.1711463114.
Article347 days agoStructural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV
Shalley N. Kudalkar, Irfan Ullah, Nicole Bertoletti, Hanna K. Mandl, José A. Cisneros, Jagadish Beloor, Albert H. Chan, Elias Quijano, W. Mark Saltzman, William L. Jorgensen, Priti Kumar, Karen S. Anderson (2019). Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV. Antiviral Research, 167, pp. 110-116, DOI: 10.1016/j.antiviral.2019.04.010.
Article347 days agoDesign, Conformation, and Crystallography of 2-Naphthyl Phenyl Ethers as Potent Anti-HIV Agents
Won‐Gil Lee, Albert H. Chan, Krasimir A. Spasov, Karen S. Anderson, William L. Jorgensen (2016). Design, Conformation, and Crystallography of 2-Naphthyl Phenyl Ethers as Potent Anti-HIV Agents. ACS Medicinal Chemistry Letters, 7(12), pp. 1156-1160, DOI: 10.1021/acsmedchemlett.6b00390.
Article347 days agoDiscovery and crystallography of bicyclic arylaminoazines as potent inhibitors of HIV-1 reverse transcriptase
Won-Gil Lee, Kathleen M. Frey, Ricardo Gallardo‐Macias, Krasimir A. Spasov, Albert H. Chan, Karen S. Anderson, William L. Jorgensen (2015). Discovery and crystallography of bicyclic arylaminoazines as potent inhibitors of HIV-1 reverse transcriptase. Bioorganic & Medicinal Chemistry Letters, 25(21), pp. 4824-4827, DOI: 10.1016/j.bmcl.2015.06.074.
Article347 days agoStructural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase
Kathleen M. Frey, Nicole Bertoletti, Albert H. Chan, Joseph A. Ippolito, Mariela Bollini, Krasimir A. Spasov, William L. Jorgensen, Karen S. Anderson (2022). Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase. Frontiers in Molecular Biosciences, 9, DOI: 10.3389/fmolb.2022.805187.
Article347 days ago