Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock
Bart Ferwerda, Santos Alonso, Kathy Banahan, Matthew B. B. McCall, Evangelos J. Giamarellos‐Bourboulis, Bart Ramakers, Maria Mouktaroudi, Pamela R. Fain, Neskuts Izagirre, Din Syafruddin, Tudor Cristea, Frank P. Mockenhaupt, Marita Troye‐Blomberg, Oliver Kumpf, Boubacar Maïga, Amagana Dolo, Ogobara K. Doumbo, Santhosh Sundaresan, George Bedu‐Addo, Reinout van Crevel, Lutz Hamann, Djin‐Ye Oh, Ralf R. Schumann, Leo A. B. Joosten, Concepción de la Rúa Vaca, Robert W. Sauerwein, Joost P.H. Drenth, Bart Jan Kullberg, André van der Ven, Adrian V. S. Hill, Peter Pickkers, Jos W.M. van der Meer, Luke O'neill, Mihai G. Netea (2009). Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock. Proceedings of the National Academy of Sciences, 106(25), pp. 10272-10277, DOI: 10.1073/pnas.0811273106.
