The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human
Robin McDougall, Diane Ramsden, Sagar Agarwal, Saket Agarwal, Krishna Aluri, Michael Arciprete, Christopher R. Brown, Elena Castellanos-Rizaldos, Klaus Charissé, Saeho Chong, Joseph A. Cichocki, Kevin Fitzgerald, Varun Goel, Yongli Gu, Dale C. Guenther, Bahru Habtemariam, Vasant Jadhav, Maja M. Janas, Muthusamy Jayaraman, Jeffrey C. Kurz, Jing Li, Ju Liu, Xiumin Liu, Steven Liou, Chris Maclauchlin, Martin A. Maier, Muthiah Manoharan, Jayaprakash K. Nair, Gabriel J. Robbie, Karyn Schmidt, Pete Smith, Christopher S. Theile, Akshay Vaishnaw, Scott Waldron, Yuanxin Xu, Xuemei Zhang, Ivan Zlatev, Jing‐Tao Wu (2021). The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human. , 50(6), DOI: https://doi.org/10.1124/dmd.121.000428.