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The last 5 uploaded publications
Broad-Spectrum Antiviral Activity of 3′-Deoxy-3′-Fluoroadenosine against Emerging Flaviviruses
Luděk Eyer, Pavel Svoboda, Jan Balvan, Tomáš Vičar, Martina Raudenská, Michal Štefánik, Jan Haviernik, Ivana Huvarová, Petra Straková, Ivo Rudolf, Zdeněk Hubálek, Katherine L. Seley‐Radtke, De Clercq Erik, Daniel Růžek (2020). Broad-Spectrum Antiviral Activity of 3′-Deoxy-3′-Fluoroadenosine against Emerging Flaviviruses. , 65(2), DOI: https://doi.org/10.1128/aac.01522-20.
Article56 days agoAn E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus in Mice
Jan Haviernik, Luděk Eyer, Antoine Nougaırède, Marie Uhlířová, Jean‐Sélim Driouich, Darina Zouharová, James J. Valdés, Ernest Gould, De Clercq Erik, Xavier de Lamballerie, Daniel Růžek (2020). An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus in Mice. , DOI: https://doi.org/10.3390/proceedings2020050012.
Article56 days agoAn E460D substitution in the NS5 protein of tick-borne encephalitis virus confers resistance to the inhibitor Galidesivir (BCX4430) and also attenuates the virus for mice
Luděk Eyer, Antoine Nougaırède, Marie Uhlířová, Jean‐Sélim Driouich, Darina Zouharová, James J. Valdés, Jan Haviernik, Ernest A. Gould, De Clercq Erik, Xavier de Lamballerie, Daniel Růžek (2019). An E460D substitution in the NS5 protein of tick-borne encephalitis virus confers resistance to the inhibitor Galidesivir (BCX4430) and also attenuates the virus for mice. , DOI: https://doi.org/10.1101/563544.
Preprint56 days agoAn E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice
Luděk Eyer, Antoine Nougaırède, Marie Uhlířová, Jean‐Sélim Driouich, Darina Zouharová, James J. Valdés, Jan Haviernik, Ernest A. Gould, De Clercq Erik, Xavier de Lamballerie, Daniel Růžek (2019). An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice. , 93(16), DOI: https://doi.org/10.1128/jvi.00367-19.
Article56 days agoAntiviral activity of the adenosine analogue BCX4430 against West Nile virus and tick-borne flaviviruses
Luděk Eyer, Darina Zouharová, Jana Širmarová, Martina Fojtíková, Michal Štefánik, Jan Haviernik, Radim Nencka, De Clercq Erik, Daniel Růžek (2017). Antiviral activity of the adenosine analogue BCX4430 against West Nile virus and tick-borne flaviviruses. , 142, DOI: https://doi.org/10.1016/j.antiviral.2017.03.012.
Article56 days ago