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The last 5 uploaded publications
Epithelial tension controls intestinal cell extrusion
Daniel Krueger, Willem Kasper Spoelstra, Dirk Jan Mastebroek, Rutger N.U. Kok, Sanlan Wu, Mikhail Nikolaev, Marie Bannier-Hélaouët, Nikolche Gjorevski, Matthias P. Lütolf, Johan H. van Es, Jeroen S. van Zon, Sander J. Tans, Hans Clevers (2025). Epithelial tension controls intestinal cell extrusion. , 389(6764), DOI: https://doi.org/10.1126/science.adr8753.
Article13 days agoBEST4/CA7<sup>+</sup> and goblet cells are interdependent regulators of intestinal mucus homeostasis
Willem Kasper Spoelstra, Daisong Wang, Johan H. van Es, Hans Clevers, Jeroen S. van Zon, Sander J. Tans (2025). BEST4/CA7<sup>+</sup> and goblet cells are interdependent regulators of intestinal mucus homeostasis. , DOI: https://doi.org/10.1101/2025.09.29.679286.
Article13 days agoInterferon-responsive intestinal BEST4/CA7+ cells are targets of bacterial diarrheal toxins
Daisong Wang, Willem Kasper Spoelstra, Lin Lin, Ninouk Akkerman, Daniel Krueger, Talya Dayton, Jeroen S. van Zon, Sander J. Tans, Johan H. van Es, Hans Clevers (2025). Interferon-responsive intestinal BEST4/CA7+ cells are targets of bacterial diarrheal toxins. , 32(4), DOI: https://doi.org/10.1016/j.stem.2025.02.003.
Article13 days agoLoss of Paneth cell contact starts a WNT differentiation timer in intestinal crypts
Jeroen S. van Zon, Rutger N.U. Kok, Xuan Zheng, Willem Kasper Spoelstra, Tinka V M Clement, Yorick van de Grift, Hans Clevers, Renée van Amerongen, Sander J. Tans (2024). Loss of Paneth cell contact starts a WNT differentiation timer in intestinal crypts. , DOI: https://doi.org/10.21203/rs.3.rs-5452594/v1.
Preprint13 days ago