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The last 5 uploaded publications
Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV
Shalley N. Kudalkar, Irfan Ullah, Nicole Bertoletti, Hanna K. Mandl, José A. Cisneros, Jagadish Beloor, Albert H. Chan, Elias Quijano, W. Mark Saltzman, William L. Jorgensen, Priti Kumar, Karen S. Anderson (2019). Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV. Antiviral Research, 167, pp. 110-116, DOI: 10.1016/j.antiviral.2019.04.010.
Article348 days agoCovalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead
Joseph A. Ippolito, Haichan Niu, Nicole Bertoletti, Zachary J. Carter, Shengyan Jin, Krasimir A. Spasov, José A. Cisneros, Margarita Valhondo, Kara J. Cutrona, Karen S. Anderson, William L. Jorgensen (2021). Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead. ACS Medicinal Chemistry Letters, 12(2), pp. 249-255, DOI: 10.1021/acsmedchemlett.0c00612.
Article348 days agoStructure-Guided Identification of DNMT3B Inhibitors
Ana S. Newton, John C. Faver, Goran Micevic, Viswanathan Muthusamy, Shalley N. Kudalkar, Nicole Bertoletti, Karen S. Anderson, Marcus Bosenberg, William L. Jorgensen (2020). Structure-Guided Identification of DNMT3B Inhibitors. ACS Medicinal Chemistry Letters, 11(5), pp. 971-976, DOI: 10.1021/acsmedchemlett.0c00011.
Article348 days agoStructural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase
Kathleen M. Frey, Nicole Bertoletti, Albert H. Chan, Joseph A. Ippolito, Mariela Bollini, Krasimir A. Spasov, William L. Jorgensen, Karen S. Anderson (2022). Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase. Frontiers in Molecular Biosciences, 9, DOI: 10.3389/fmolb.2022.805187.
Article348 days ago