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The last 5 uploaded publications
Proof-of-concept studies with a computationally designed M <sup>pro</sup> inhibitor as a synergistic combination regimen alternative to Paxlovid
Christina Papini, Irfan Ullah, Amalendu P. Ranjan, Shuo Zhang, Qihao Wu, Krasimir A. Spasov, Chunhui Zhang, Walther Mothes, Jason M. Crawford, Brett D. Lindenbach, Pradeep D. Uchil, Priti Kumar, William L. Jorgensen, Karen S. Anderson (2024). Proof-of-concept studies with a computationally designed M <sup>pro</sup> inhibitor as a synergistic combination regimen alternative to Paxlovid. Proceedings of the National Academy of Sciences, 121(17), DOI: 10.1073/pnas.2320713121.
Article360 days agoA nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium
Anindita Mukerjee, Pinar Iyidogan, Alejandro Castellanos-González, José A. Cisneros, Daniel J. Czyzyk, Amalendu P. Ranjan, William L. Jorgensen, A. Clinton White, Jamboor K. Vishwanatha, Karen S. Anderson (2015). A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium. Bioorganic & Medicinal Chemistry Letters, 25(10), pp. 2065-2067, DOI: 10.1016/j.bmcl.2015.03.091.
Article360 days agoProdrug Nanotherapy Demonstrate In Vivo Anticryptosporidial Efficacy in a Mouse Model of Chronic Cryptosporidium Infection
Amalendu P. Ranjan, Daniel J. Czyzyk, Griselle Martinez-Traverso, Aygül Sadıqova, Margarita Valhondo, Deborah A. Schaefer, Krasimir A. Spasov, William L. Jorgensen, Jamboor K. Vishwanatha, Michael W. Riggs, Alejandro Castellanos-González, Karen S. Anderson (2024). Prodrug Nanotherapy Demonstrate In Vivo Anticryptosporidial Efficacy in a Mouse Model of Chronic Cryptosporidium Infection. RSC Pharmaceutics, DOI: 10.1039/d4pm00093e.
Article360 days ago