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The last 5 uploaded publications
Mutations in BAP1 drive tumour sensitivity to programmed cell death in patient-derived cholangiocarcinoma orgnaoids
Shaojun Shi, Imre F. Schene, Indi P. Joore, Henk P. Roest, Gilles van Tienderen, Ruby Lieshout, Bas Groot Koerkamp, Petra E. de Ruiter, Benedetta Artegiani, Sabine A. Fuchs, Hans Clevers, Luc J. W. van der Laan, Monique M.A. Verstegen (2022). Mutations in BAP1 drive tumour sensitivity to programmed cell death in patient-derived cholangiocarcinoma orgnaoids. , 77, DOI: https://doi.org/10.1016/s0168-8278(22)01621-x.
Article35 days agoBipotent Liver Progenitors Depend on Glycolysis and Mitochondrial Pyruvate Oxidation for Stem Cell Functions
Imre F. Schene, Rúben J. Ramos, Anke H.M. van Vugt, Hoa Truong, D.J. van den Heuvel, Hans C. Gerritsen, Riekelt H. Houtkooper, Michel van Weeghel, Sabine Middendorp, Michal Mokrý, Bart Spee, Kerstin Schneeberger, Peter G. J. Nikkels, Meritxell Huch, Hans Clevers, Edward E. S. Nieuwenhuis, Peter M. van Hasselt, Sabine A. Fuchs (2020). Bipotent Liver Progenitors Depend on Glycolysis and Mitochondrial Pyruvate Oxidation for Stem Cell Functions. , DOI: https://doi.org/10.2139/ssrn.3564994.
Article24 days agoHuman extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease
Monique M.A. Verstegen, Floris J.M. Roos, Ksenia Burka, Helmuth Gehart, Myrthe Jager, Maaike de Wolf, Marcel J. C. Bijvelds, Hugo R de Jonge, Arif I. Ardisasmita, Nick A. van Huizen, Henk P. Roest, Jeroen de Jonge, Michael Koch, Francesco Pampaloni, Sabine A. Fuchs, Imre F. Schene, Theo M. Luider, Hubert P.J. van der Doef, Frank A J A Bodewes, Ruben H. J. de Kleine, Bart Spee, Gert-Jan Kremers, Hans Clevers, Jan N.M. IJzermans, Edwin Cuppen, Luc J. W. van der Laan, Monique M.A. Verstegen, Floris J.M. Roos, Ksenia Burka, Helmuth Gehart, Myrthe Jager, Maaike de Wolf, Marcel J. C. Bijvelds, Hugo R de Jonge, Arif I. Ardisasmita, Nick A. van Huizen, Henk P. Roest, Jeroen de Jonge, Michael Koch, Francesco Pampaloni, Sabine A. Fuchs, Imre F. Schene, Theo M. Luider, Hubert P.J. van der Doef, Frank A J A Bodewes, Ruben H. J. de Kleine, Bart Spee, Gert-Jan Kremers, Hans Clevers, Jan N.M. IJzermans, Edwin Cuppen, Luc J. W. van der Laan (2020). Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease. , 10(1), DOI: https://doi.org/10.1038/s41598-020-79082-8.
Article24 days agoHuman extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease
Monique M.A. Verstegen, Floris J.M. Roos, Ksenia Burka, Helmuth Gehart, Myrthe Jager, Maaike de Wolf, Marcel J. C. Bijvelds, Hugo R de Jonge, Arif I. Ardisasmita, Nick A. van Huizen, Henk P. Roest, Jeroen de Jonge, Michael Koch, Francesco Pampaloni, Sabine A. Fuchs, Imre F. Schene, Theo M. Luider, Hubert P.J. van der Doef, Frank A J A Bodewes, Ruben H. J. de Kleine, Bart Spee, Gert-Jan Kremers, Hans Clevers, Jan N.M. IJzermans, Edwin Cuppen, Luc J. W. van der Laan, Monique M.A. Verstegen, Floris J.M. Roos, Ksenia Burka, Helmuth Gehart, Myrthe Jager, Maaike de Wolf, Marcel J. C. Bijvelds, Hugo R de Jonge, Arif I. Ardisasmita, Nick A. van Huizen, Henk P. Roest, Jeroen de Jonge, Michael Koch, Francesco Pampaloni, Sabine A. Fuchs, Imre F. Schene, Theo M. Luider, Hubert P.J. van der Doef, Frank A J A Bodewes, Ruben H. J. de Kleine, Bart Spee, Gert-Jan Kremers, Hans Clevers, Jan N.M. IJzermans, Edwin Cuppen, Luc J. W. van der Laan (2020). Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease. , 10(1), DOI: https://doi.org/10.1038/s41598-020-79082-8.
Article24 days agoLarge‐Scale Production of LGR5‐Positive Bipotential Human Liver Stem Cells
Kerstin Schneeberger, Natalia Sánchez‐Romero, Shicheng Ye, Frank G. van Steenbeek, Loes A. Oosterhoff, Iris Plá Palacín, Chen Chen, Monique E. van Wolferen, Gilles van Tienderen, Ruby Lieshout, Haaike Colemonts‐Vroninks, Imre F. Schene, Ruurdtje Hoekstra, Monique M.A. Verstegen, Luc J. W. van der Laan, Louis C. Penning, Sabine A. Fuchs, Hans Clevers, Joery De Kock, Pedro M. Baptista, Bart Spee (2019). Large‐Scale Production of LGR5‐Positive Bipotential Human Liver Stem Cells. , 72(1), DOI: https://doi.org/10.1002/hep.31037.
Article24 days ago