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The last 5 uploaded publications
Myocardial Ischemia/Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti–Toll-Like Receptor-2 Antibody
Fatih Arslan, Mirjam B. Smeets, Luke O'neill, Brian Keogh, Peter McGuirk, Leo Timmers, Claudia Tersteeg, Imo E. Hoefer, Pieter A. Doevendans, Gerard Pasterkamp, Dominique P.V. de Kleijn (2009). Myocardial Ischemia/Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti–Toll-Like Receptor-2 Antibody. Circulation, 121(1), pp. 80-90, DOI: 10.1161/circulationaha.109.880187.
Article246 days agoA Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins
Anthony W. Ryan, Mark Lynch, Sinead Smith, Sylvie Amu, Hendrik J. Nel, Claire E. McCoy, Jennifer K. Dowling, Eve Draper, Vincent O’Reilly, Ciara McCarthy, Julie O’Brien, Déirdre Ní Eidhin, Mary J. O’Connell, Brian Keogh, Oliver Morton, Thomas R. Rogers, Padraic G. Fallon, Luke O'neill, Dermot Kelleher, Christine E. Loscher (2011). A Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins. PLoS Pathogens, 7(6), pp. e1002076-e1002076, DOI: 10.1371/journal.ppat.1002076.
Article246 days agoTreatment With OPN-305, a Humanized Anti–Toll-Like Receptor-2 Antibody, Reduces Myocardial Ischemia/Reperfusion Injury in Pigs
Fatih Arslan, Jaco H. Houtgraaf, Brian Keogh, Kushan Kazemi, Renate de Jong, William McCormack, Luke O'neill, Peter McGuirk, Leo Timmers, Mirjam B. Smeets, Lars Akeroyd, Mary M. Reilly, Gerard Pasterkamp, Dominique P.V. de Kleijn (2012). Treatment With OPN-305, a Humanized Anti–Toll-Like Receptor-2 Antibody, Reduces Myocardial Ischemia/Reperfusion Injury in Pigs. Circulation Cardiovascular Interventions, 5(2), pp. 279-287, DOI: 10.1161/circinterventions.111.967596.
Article246 days agoBlockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures
Sinéad Nic An Ultaigh, Tajvur P Saber, Jennifer McCormick, M. Kari Connolly, Jérôme Dellacasagrande, Brian Keogh, William McCormack, Mary M. Reilly, Luke O'neill, Peter McGuirk, Ursula Fearon, Douglas J. Veale (2011). Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures. Arthritis Research & Therapy, 13(1), DOI: 10.1186/ar3261.
Article246 days ago