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The last 5 uploaded publications
Skeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle
Guillaume Tournaire, Shauni Loopmans, Steve Stegen, Gianmarco Rinaldi, Guy Eelen, Sophie Torrekens, Karen Moermans, Peter Carmeliet, Bart Ghesquière, Bernard Thienpont, Sarah‐Maria Fendt, Nick van Gastel, Geert Carmeliet (2022). Skeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle. , 40(4), DOI: https://doi.org/10.1016/j.celrep.2022.111105.
Article64 days agoDe novo serine synthesis regulates chondrocyte proliferation during bone development and repair
Steve Stegen, Shauni Loopmans, Ingrid Stockmans, Karen Moermans, Peter Carmeliet, Geert Carmeliet (2022). De novo serine synthesis regulates chondrocyte proliferation during bone development and repair. , 10(1), DOI: https://doi.org/10.1038/s41413-021-00185-7.
Article64 days agoThe pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes
Shauni Loopmans, Kateřina Rohlenová, Thomas Van Brussel, Ingrid Stockmans, Karen Moermans, Nicolas Peredo, Peter Carmeliet, Diether Lambrechts, Steve Stegen, Geert Carmeliet (2025). The pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes. , 7(1), DOI: https://doi.org/10.1038/s42255-024-01187-5.
Article64 days agoGlucose metabolism via the pentose phosphate pathway controls chondrocyte survival and proteostasis during bone development
Shauni Loopmans, Steve Stegen, Ingrid Stockmans, Karen Moermans, Peter Carmeliet, Geert Carmeliet (2021). Glucose metabolism via the pentose phosphate pathway controls chondrocyte survival and proteostasis during bone development. , 14, DOI: https://doi.org/10.1016/j.bonr.2021.100814.
Article64 days agoGlucose metabolism prevents ferroptosis and secures proteostasis in the developing growth plate
Shauni Loopmans, Steve Stegen, Kateřina Rohlenová, Ingrid Stockmans, Karen Moermans, Peter Carmeliet, Geert Carmeliet (2022). Glucose metabolism prevents ferroptosis and secures proteostasis in the developing growth plate. , 16, DOI: https://doi.org/10.1016/j.bonr.2022.101189.
Article64 days ago