Structure-based design of novel 2,4,5-trisubstituted pyrimidine derivatives as potent HIV-1 NNRTIs by exploiting the tolerant regions in NNTRIs binding pocket
Zhenzhen Zhou, Minghui Xie, Zongji Zhuo, Yalin Wang, Fabao Zhao, Sining Tao, Zhening Liang, De Clercq Erik, Christophe Pannecouque, Shujing Xu, Dongwei Kang, Xinyong Liu (2025). Structure-based design of novel 2,4,5-trisubstituted pyrimidine derivatives as potent HIV-1 NNRTIs by exploiting the tolerant regions in NNTRIs binding pocket. , 289, DOI: https://doi.org/10.1016/j.ejmech.2025.117464.