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The last 5 uploaded publications
216eP MegaMOST - A multicenter, open-label, molecularly selected bayesian phase II platform trial in advanced or metastatic solid tumors: Final analysis of the trametinib cohort
Olivier Trédan, E.B. Saada, Cécile Dalban, Sophie Cousin, A. Le Cesne, A. Italiano, François Bertucci, C.A. Gomez-Roca, Lauriane Eberst, I. L. Ray-Coquard, Loïc Verlingue, P. Cassier, Valéry Attignon, Sylvie Chabaud, Romaine Mayet, E. Cauquil, G. Garin, David Pérol, Jean Yves Blay (2025). 216eP MegaMOST - A multicenter, open-label, molecularly selected bayesian phase II platform trial in advanced or metastatic solid tumors: Final analysis of the trametinib cohort. , 36, DOI: https://doi.org/10.1016/j.annonc.2025.08.648.
Article15 days agoEstablishing a living biobank of pediatric high-grade glioma and ependymoma suitable for cancer pharmacology
Clémence Deligne, Arthur Tourbez, Flavie Bénard, Swann Meyer, Armin Curt, Matteo Gianesello, Maud Hamadou, Laurent Clavier, Claire Coquet, C Bocquet, Julia Tomine, Thomas Diot, Hermes Paraqindes, Virginie Marcel, Clément Berthelot, J. Engel, Isabelle Rochet, Marc Barritault, Clara Savary, Nicolas Gadot, Valéry Attignon, Marjorie Carrère, Marc Billaud, Aurélie Dutour, Martine Cordier–Bussat, P.A. Beuriat, Alexandru Szathmári, Federico Di Rocco, Jean Yves Blay, Luca Tiberi, Alexandre Vasiljevic, David Meyronet, Marie Castets, Pierre Leblond, Laura Broutier (2025). Establishing a living biobank of pediatric high-grade glioma and ependymoma suitable for cancer pharmacology. , 27(5), DOI: https://doi.org/10.1093/neuonc/noaf007.
Article15 days agoBroad versus limited gene panels to guide treatment in patients with advanced solid tumors: a randomized controlled trial
Olivier Trédan, Damien Pouessel, Nicolas Penel, Sylvie Chabaud, Carlos Gomez‐Roca, Jean-Pierre Delord, Diane Pannier, Mehdi Brahmi, Michel Fabbro, Marie-Eve Garcia, Delphine Larrieu‐Ciron, Isabelle Ray‐Coquard, Marie Viala, Antoîne Italiano, Diégo Tosi, Philippe A. Cassier, Armelle Dufresne, Valéry Attignon, Sandrine Boyault, Isabelle Treilleux, Alain Viari, David Pérol, Jean Yves Blay (2025). Broad versus limited gene panels to guide treatment in patients with advanced solid tumors: a randomized controlled trial. , 31(5), DOI: https://doi.org/10.1038/s41591-025-03613-x.
Article15 days agoAbstract 6360: A tumor agnostic composite gene expression signature identifies three groups of patients treated with immune checkpoint blockade with distinct clinical outcome
Mehdi Lamkhioued, Guillaume Robert-Siegwald, Roxane M. Pommier, David M. Tricoli, Camille Brodin, Valéry Attignon, Nicolas Gadot, Séverine Tabone‐Eglinger, F.N. Jerome, Aurélie Swalduz, Isabelle Ray‐Coquard, Eve‐Marie Neidhardt, Clélia Coutzac, Loïc Verlingue, Olivier Trédan, Jean Yves Blay, Christophe Caux, Alain Viari, Nicolas Poirier, Aurore Morello, Isabelle Girault, Pierre Saintigny (2025). Abstract 6360: A tumor agnostic composite gene expression signature identifies three groups of patients treated with immune checkpoint blockade with distinct clinical outcome. , 85(8_Supplement_1), DOI: https://doi.org/10.1158/1538-7445.am2025-6360.
Article15 days agoBMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas
Paul Huchedé, Swann Meyer, Clément Berthelot, Maud Hamadou, Adrien Bertrand‐Chapel, Andria Rakotomalala, Line Manceau, Julia Tomine, Nicolas Lespinasse, Paul Lewandowski, Martine Cordier–Bussat, Laura Broutier, Aurélie Dutour, Isabelle Rochet, Jean Yves Blay, Cyril Dégletagne, Valéry Attignon, Angel Montero-Carcaboso, Marion Le Grand, Eddy Pasquier, Alexandre Vasiljevic, Pascale Gilardi‐Hebenstreit, Samuel Meignan, Pierre Leblond, Vanessa Ribes, Érika Cosset, Marie Castets (2024). BMP2 and BMP7 cooperate with H3.3K27M to promote quiescence and invasiveness in pediatric diffuse midline gliomas. , 12, DOI: https://doi.org/10.7554/elife.91313.3.
Article15 days ago