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The last 5 uploaded publications
Mitochondria-targeted antioxidants and metabolic modulators as pharmacological interventions to slow ageing
Jan Gruber, Sheng Fong, Ce-Belle Chen, Sialee Yoong, Giorgia Pastorin, Sebastian Schaffer, Irwin K. Cheah, Barry Halliwell (2012). Mitochondria-targeted antioxidants and metabolic modulators as pharmacological interventions to slow ageing. Biotechnology Advances, 31(5), pp. 563-592, DOI: 10.1016/j.biotechadv.2012.09.005.
Article228 days agoEnergy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model
Sheng Fong, Emelyne Teo, Li Fang Ng, Ce-Belle Chen, Lakshmi Narayanan Lakshmanan, Sau Yee Tsoi, Philip K. Moore, Takao Inoue, Barry Halliwell, Jan Gruber (2016). Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model. Scientific Reports, 6(1), DOI: 10.1038/srep33781.
Article228 days agoAgeing in nematodes: do antioxidants extend lifespan in Caenorhabditis elegans?
Pamela Boon Li Pun, Jan Gruber, Soon Yew Tang, Sebastian Schaffer, Raphael Lee Sheng Ong, Sheng Fong, Li Fang Ng, Irwin K. Cheah, Barry Halliwell (2009). Ageing in nematodes: do antioxidants extend lifespan in Caenorhabditis elegans?. Biogerontology, 11(1), pp. 17-30, DOI: 10.1007/s10522-009-9223-5.
Article228 days agoMitochondrial Changes in Ageing Caenorhabditis elegans – What Do We Learn from Superoxide Dismutase Knockouts?
Jan Gruber, Li Fang Ng, Sheng Fong, Yee Ting Wong, Soon Ann Koh, Ce-Belle Chen, Guanghou Shui, Wei Fun Cheong, Sebastian Schaffer, Markus R. Wenk, Barry Halliwell (2011). Mitochondrial Changes in Ageing Caenorhabditis elegans – What Do We Learn from Superoxide Dismutase Knockouts?. PLoS ONE, 6(5), pp. e19444-e19444, DOI: 10.1371/journal.pone.0019444.
Article228 days agoMetabolic stress is a primary pathogenic event in transgenic Caenorhabditis elegans expressing pan-neuronal human amyloid beta
Emelyne Teo, Sudharshan Ravi, Diogo Barardo, Hyung-Seok Kim, Sheng Fong, Amaury Cazenave‐Gassiot, Tsze Yin Tan, Jianhong Ching, Jean‐Paul Kovalik, Markus R. Wenk, Rudiyanto Gunawan, Philip K. Moore, Barry Halliwell, Nicholas S. Tolwinski, Jan Gruber (2019). Metabolic stress is a primary pathogenic event in transgenic Caenorhabditis elegans expressing pan-neuronal human amyloid beta. eLife, 8, DOI: 10.7554/elife.50069.
Article228 days ago