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The last 5 uploaded publications
Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1α expression
Robert N. Jones, Kate E. McDonald, Joseph Willson, Bart Ghesquière, David Sammut, Eleni Daniel, A.J. Harris, Amy Lewis, A. A. Roger Thompson, Rebecca Dickinson, Tracie Plant, Fiona Murphy, Pranvera Sadiku, Brian Keevil, Peter Carmeliet, Moira K. B. Whyte, John Newell‐Price, Sarah R. Walmsley (2016). Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1α expression. , 127(21), DOI: https://doi.org/10.1182/blood-2016-02-696922.
Letter73 days agoProlyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
Sarah R. Walmsley, Edwin R. Chilvers, A. A. Roger Thompson, Kathryn Vaughan, Helen M. Marriott, Lisa C. Parker, Gary S. Shaw, Selina Parmar, Martin Schneider, Ian Sabroe, David H. Dockrell, Marta Milo, Cormac T. Taylor, Randall S. Johnson, Christopher W. Pugh, Peter J. Ratcliffe, Patrick H. Maxwell, Peter Carmeliet, Moira K. B. Whyte (2011). Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice. , 121(3), DOI: https://doi.org/10.1172/jci43273.
Article73 days agoProlyl Hydroxylase Phd3 Is Essential For Hypoxic Regulation Of Neutrophilic Inflammation
Sarah R. Walmsley, Edwin R. Chilvers, A. A. Roger Thompson, Kathryn Vaughan, Helen M. Marriott, Lisa C. Parker, Gary S. Shaw, Selina Parmar, Martin Schneider, Ian Sabroe, David H. Dockrell, Marta Milo, Cormac T. Taylor, Randall S. Johnson, Christopher W. Pugh, Peter J. Ratcliffe, Patrick H. Maxwell, Peter Carmeliet, Moira K. B. Whyte (2011). Prolyl Hydroxylase Phd3 Is Essential For Hypoxic Regulation Of Neutrophilic Inflammation. , DOI: https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4009.
Article73 days agoProlyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses
Pranvera Sadiku, Joseph Willson, Rebecca Dickinson, Fiona Murphy, A.J. Harris, Amy Lewis, David Sammut, Ananda S. Mirchandani, Eilíse M. Ryan, Emily Watts, A. A. Roger Thompson, Helen M. Marriott, David H. Dockrell, Cormac T. Taylor, Martin Schneider, Patrick H. Maxwell, Edwin R. Chilvers, Massimiliano Mazzone, Verónica M. Dardé, Christopher W. Pugh, Peter J. Ratcliffe, Christopher J. Schofield, Bart Ghesquière, Peter Carmeliet, Moira K. B. Whyte, Sarah R. Walmsley (2017). Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses. , 127(9), DOI: https://doi.org/10.1172/jci90848.
Article73 days agoHypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism
A. A. Roger Thompson, Rebecca Dickinson, Fiona Murphy, John P. Thomson, Helen M. Marriott, Adriana Tavares, Joseph Willson, Lynne Williams, Amy Lewis, Ananda S. Mirchandani, Patricia Dos Santos Coelho, Catherine Doherty, Eilíse M. Ryan, Emily Watts, Nicholas M. Morton, Shareen Forbes, Roland H. Stimson, Abdul Hameed, Nadine Arnold, Julie A. Preston, Allan Lawrie, Veronica Finisguerra, Massimiliano Mazzone, Pranvera Sadiku, Jermaine Goveia, Federico Taverna, Peter Carmeliet, Simon J. Foster, Edwin R. Chilvers, Andrew S. Cowburn, David H. Dockrell, Randall S. Johnson, Richard R. Meehan, Moira K. B. Whyte, Sarah R. Walmsley (2017). Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism. , 2(8), DOI: https://doi.org/10.1126/sciimmunol.aal2861.
Article73 days ago