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The last 5 uploaded publications
Protocol for the generation and differentiation of thymic epithelial organoids from adult mouse thymus tissue
Sam Willemsen, Ni Luh Wisma Eka Yanti, Johan H. van Es, Hans Clevers, Sang-Ho Lim (2025). Protocol for the generation and differentiation of thymic epithelial organoids from adult mouse thymus tissue. , 6(2), DOI: https://doi.org/10.1016/j.xpro.2025.103883.
Article15 days agoEpidermal growth factor receptor (EGFR) is a target of the tumor-suppressor E3 ligase FBXW7
Matteo Boretto, Maarten H. Geurts, Shashank Gandhi, Ma Ziliang, Nadzeya Staliarova, Martina Celotti, Sang-Ho Lim, Gui-Wei He, Rosemary Millen, Else Driehuis, Harry Begthel, Lidwien Smabers, Jeanine Roodhart, Johan van Es, Wei Wu, Hans Clevers, Matteo Boretto, Maarten H. Geurts, Shashank Gandhi, Ma Ziliang, Nadzeya Staliarova, Martina Celotti, Sang-Ho Lim, Gui-Wei He, Rosemary Millen, Else Driehuis, Harry Begthel, Lidwien Smabers, Jeanine Roodhart, Johan van Es, Wei Wu, Hans Clevers (2024). Epidermal growth factor receptor (EGFR) is a target of the tumor-suppressor E3 ligase FBXW7. , 121(12), DOI: https://doi.org/10.1073/pnas.2309902121.
Article15 days agoEpidermal growth factor receptor (EGFR) is a target of the tumor-suppressor E3 ligase FBXW7
Matteo Boretto, Maarten H. Geurts, Shashank Gandhi, Ma Ziliang, Nadzeya Staliarova, Martina Celotti, Sang-Ho Lim, Gui-Wei He, Rosemary Millen, Else Driehuis, Harry Begthel, Lidwien Smabers, Jeanine Roodhart, Johan van Es, Wei Wu, Hans Clevers, Matteo Boretto, Maarten H. Geurts, Shashank Gandhi, Ma Ziliang, Nadzeya Staliarova, Martina Celotti, Sang-Ho Lim, Gui-Wei He, Rosemary Millen, Else Driehuis, Harry Begthel, Lidwien Smabers, Jeanine Roodhart, Johan van Es, Wei Wu, Hans Clevers (2024). Epidermal growth factor receptor (EGFR) is a target of the tumor-suppressor E3 ligase FBXW7. , 121(12), DOI: https://doi.org/10.1073/pnas.2309902121.
Article15 days agoIntegrin-activating <i>Yersinia</i> protein Invasin sustains long-term expansion of primary epithelial cells as 2D organoid sheets
Joost J.A.P.M. Wijnakker, Gijs J. F. van Son, Daniel Krueger, Willine J. van de Wetering, Carmen López-Iglesias, Robin Schreurs, Fenna van Rijt, Sang-Ho Lim, Lin Lin, Peter J. Peters, Ralph R. Isberg, Claudia Y. Janda, Wim de Lau, Hans Clevers (2024). Integrin-activating <i>Yersinia</i> protein Invasin sustains long-term expansion of primary epithelial cells as 2D organoid sheets. , 122(1), DOI: https://doi.org/10.1073/pnas.2420595121.
Article15 days agoRecapitulating the adenoma–carcinoma sequence by selection of four spontaneous oncogenic mutations in mismatch-repair-deficient human colon organoids
Tomohiro Mizutani, Matteo Boretto, Sang-Ho Lim, Jarno Drost, Diego Montiel González, Rurika Oka, Maarten H. Geurts, Harry Begthel, Jeroen Korving, Johan H. van Es, Ruben van Boxtel, Hans Clevers, Tomohiro Mizutani, Matteo Boretto, Sang-Ho Lim, Jarno Drost, Diego Montiel González, Rurika Oka, Maarten H. Geurts, Harry Begthel, Jeroen Korving, Johan H. van Es, Ruben van Boxtel, Hans Clevers (2024). Recapitulating the adenoma–carcinoma sequence by selection of four spontaneous oncogenic mutations in mismatch-repair-deficient human colon organoids. , 5(12), DOI: https://doi.org/10.1038/s43018-024-00841-x.
Article15 days ago