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The last 5 uploaded publications
Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics
Robin N. Beaumont, Nicole M. Warrington, Alana Cavadino, Jessica Tyrrell, Michael Nodzenski, Momoko Horikoshi, Frank Geller, Ronny Myhre, Rebecca C. Richmond, Lavinia Paternoster, Jonathan P. Bradfield, Eskil Kreiner‐Møller, Ville Huikari, Sarah Metrustry, Kathryn L. Lunetta, Jodie N. Painter, Jouke‐Jan Hottenga, Catherine Allard, Sheila J. Barton, Ana Espinosa, Julie Marsh, Catherine Potter, Ge Zhang, Wei Ang, Diane J. Berry, Luigi Bouchard, Shikta Das, Hákon Hákonarson, Jani Heikkinen, Øyvind Helgeland, Berthold Hocher, Albert Hofman, Hazel Inskip, Samuel E. Jones, Manolis Kogevinas, Penelope A. Lind, Letizia Marullo, Sarah E. Medland, Anna Murray, Jeffrey C. Murray, Pål R. Njølstad, Ellen A. Nøhr, Christoph Reichetzeder, Susan M. Ring, Katherine S. Ruth, Loreto Santa‐Marina, Denise Scholtens, Sylvain Sebért, Verena Sengpiel, Marcus A. Tuke, Marc Vaudel, Michael N. Weedon, Gonneke Willemsen, Andrew R. Wood, Hanieh Yaghootkar, Louis J. Muglia, Meike Bartels, Caroline L. Relton, Craig E. Pennell, Leda Chatzi, Xavier Estivill, John W. Holloway, Dorret I. Boomsma, Grant W. Montgomery, Joanne M. Murabito, Tim D. Spector, Christine Power, Paul M Ridker, Hans Bisgaard, Struan F.A. Grant, Thorkild I. A. Sørensen, Vincent W.V. Jaddoe, Bo Jacobsson, Mads Melbye, Mark I. McCarthy, Andrew T. Hattersley, M. Geoffrey Hayes, Timothy M. Frayling, Marie‐France Hivert, Janine F. Felix, Elina Hyppönen, William L. Lowe, David M. Evans, Debbie A. Lawlor, Bjarke Feenstra, Rachel M. Freathy (2018). Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. , 27(4), DOI: https://doi.org/10.1093/hmg/ddx429.
Article242 days agoGenetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes
John R. B. Perry, Michael N. Weedon, Claudia Langenberg, Anne Jackson, Valeriya Lyssenko, Thomas Sparsø, Guðmar Þorleifsson, Harald Grallert, Luigi Ferrucci, Marcello Maggio, Giuseppe Paolisso, Mark Walker, Nicholette D. Palmer, Felicity Payne, Elizabeth Young, Christian Herder, Narisu Narisu, Mario A. Morken, Lori L. Bonnycastle, Katharine R. Owen, Beverley M. Shields, Beatrice Knight, Amanda J. Bennett, Christopher J. Groves, Aimo Ruokonen, Paul M Ridker, Ewan R. Pearson, Laura Pascoe, Ele Ferrannini, Stefan R. Bornstein, Heather M. Stringham, Laura J. Scott, Johanna Kuusisto, Peter M. Nilsson, Malin Neptin, Anette P. Gjesing, Charlotta Pisinger, Torsten Lauritzen, Annelli Sandbæk, Mike Sampson, Eleftheria Zeggini, Cecilia M. Lindgren, Valgerður Steinthórsdóttir, Unnur Þorsteinsdóttir, Torben Hansen, Peter Schwarz, Thomas Illig, Markku Laakso, Hreinn Stefánsson, Andrew D. Morris, Leif Groop, Oluf Pedersen, Michael Boehnke, Inês Barroso, Nicholas J. Wareham, Andrew T. Hattersley, Mark I. McCarthy, Timothy M. Frayling (2009). Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. , 19(3), DOI: https://doi.org/10.1093/hmg/ddp522.
Article242 days agoCommon variation in the FTO (fused toes) gene is strongly associated with adiposity measures in the northern finnish birth cohort of 1966
AJ Bennett, Michael N. Weedon, Eleftheria Zeggini, Rachel M. Freathy, C M Lindgren, Ulla Sovio, Nicholas J. Timpson, A Ruokonen, Hannu Martikainen, Anneli Pouta, A L Hartikainen, Timothy M. Frayling, Andrew T. Hattersley, Paul M Ridker, M I McCarthy (2007). Common variation in the FTO (fused toes) gene is strongly associated with adiposity measures in the northern finnish birth cohort of 1966. , 50
Article242 days agoType 2 Diabetes TCF7L2 Risk Genotypes Alter Birth Weight: A Study of 24,053 Individuals
Rachel M. Freathy, Michael N. Weedon, Amanda J. Bennett, Elina Hyppönen, Caroline L. Relton, Beatrice Knight, Beverley M. Shields, Kirstie Parnell, Christopher J. Groves, Susan M. Ring, Marcus Pembrey, Yoav Ben‐Shlomo, David P. Strachan, Chris Power, Paul M Ridker, Mark I. McCarthy, George Davey Smith, Andrew T. Hattersley, Timothy M. Frayling (2007). Type 2 Diabetes TCF7L2 Risk Genotypes Alter Birth Weight: A Study of 24,053 Individuals. , 80(6), DOI: https://doi.org/10.1086/518517.
Article242 days agoA Common Variant in the <i>FTO</i> Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity
Timothy M. Frayling, Nicholas J. Timpson, Michael N. Weedon, Eleftheria Zeggini, Rachel M. Freathy, Cecilia M. Lindgren, John R. B. Perry, Katherine S. Elliott, Hana Lango Allen, Nigel W. Rayner, Beverley M. Shields, Lorna W. Harries, Jeffrey C. Barrett, Sian Ellard, Christopher J. Groves, Bridget Knight, Ann‐Marie Patch, Andy Ness, Shah Ebrahim, Debbie A. Lawlor, Susan M. Ring, Yoav Ben‐Shlomo, Paul M Ridker, Ulla Sovio, Amanda J. Bennett, David Melzer, Luigi Ferrucci, Ruth J. F. Loos, Inês Barroso, Nicholas J. Wareham, Fredrik Karpe, Katharine R. Owen, Lon R. Cardon, Mark Walker, G. A. Hitman, Nicholette D. Palmer, Alex S. F. Doney, Andrew D. Morris, George Davey Smith, Andrew T. Hattersley, Mark I. McCarthy (2007). A Common Variant in the <i>FTO</i> Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity. , 316(5826), DOI: https://doi.org/10.1126/science.1141634.
Article242 days ago