Bio
We haven't found any bio for you yet.
Researcher Links
Loading links...
Publications by Type
Loading publications…
The last 5 uploaded publications
4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP)
Erden Banoğlu, Erşan Çelikoğlu, Susanna Völker, Abdurrahman Olğaç, Jana Gerstmeier, Ulrike Garscha, Burcu Çalışkan, Ulrich Sigmar Schubert, Andrea Carotti, Antonio Macchiarulo, Oliver Werz (2016). 4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP). , 113, DOI: https://doi.org/10.1016/j.ejmech.2016.02.027.
Article53 days agoIdentification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7
Tuğçe Gür Maz, Burcu Çalışkan, Ulrike Garscha, Abdurrahman Olğaç, Ulrich Sigmar Schubert, Jana Gerstmeier, Oliver Werz, Erden Banoğlu (2018). Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7. , 150, DOI: https://doi.org/10.1016/j.ejmech.2018.03.045.
Article53 days agoEnhanced Efficiency of the Microsomal Prostaglandin E <sub>2</sub> Synthase-1 Inhibitor AGU661 in Human Whole Blood by Encapsulation into PLGA-Based Nanoparticles
Philipp Dahlke, Paul M. Jordan, Lea C. Klepsch, Azize Gizem Ergül, Steffi Stumpf, Stephanie Hoeppener, Antje Vollrath, Burcu Çalışkan, Erden Banoğlu, Ulrich Sigmar Schubert, Oliver Werz (2025). Enhanced Efficiency of the Microsomal Prostaglandin E <sub>2</sub> Synthase-1 Inhibitor AGU661 in Human Whole Blood by Encapsulation into PLGA-Based Nanoparticles. , 22(11), DOI: https://doi.org/10.1021/acs.molpharmaceut.5c00766.
Article53 days agoBRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly
Ulrike Garscha, Susanna Voelker, Simona Pace, Jana Gerstmeier, Besa Emini Veseli, Stefanie Liening, Antonietta Rossi, Christina Weinigel, Silke Rummler, Ulrich Sigmar Schubert, Gerhard K. E. Scriba, Erşan Çelikoğlu, Burcu Çalışkan, Erden Banoğlu, Lidia Sautebin, Oliver Werz (2016). BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly. , 119, DOI: https://doi.org/10.1016/j.bcp.2016.08.023.
Article53 days agoSimple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacy
Tuğba Gürses, Abdurrahman Olğaç, Ulrike Garscha, Tuğçe Gür Maz, Nur Banu Bal, Orhan Uludağ, Burcu Çalışkan, Ulrich Sigmar Schubert, Oliver Werz, Erden Banoğlu (2021). Simple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacy. , 112, DOI: https://doi.org/10.1016/j.bioorg.2021.104861.
Article53 days ago