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The last 5 uploaded publications
Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments
Yuzhou Feng, Tianpei Yang, John Zhu, Mabel Li, Maria Doyle, Volkan Ozcoban, Greg Bass, Angela Pizzolla, Lachlan D. Cain, Sirui Weng, Anupama Pasam, Nikolce Kocovski, Yu‐Kuan Huang, Simon P. Keam, Terence P. Speed, Paul J. Neeson, Richard B. Pearson, Shahneen Sandhu, David L. Goode, Anna Trigos (2023). Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments. , 14(1), DOI: https://doi.org/10.1038/s41467-023-37822-0.
Article153 days agoModelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss
Javier Octavio Mejía-Hernández, Simon P. Keam, Reem Saleh, Fenella Muntz, Stephen B. Fox, David J. Byrne, Arielle Kogan, Lokman Pang, Jennifer Huynh, Cassandra Litchfield, Franco Caramia, Guillermina Lozano, Hua He, James M. You, Shahneen Sandhu, Scott Williams, Ygal Haupt, Sue Haupt (2022). Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss. , 13(9), DOI: https://doi.org/10.1038/s41419-022-05211-y.
Article153 days agoTargeting MDM4 as a Novel Therapeutic Approach in Prostate Cancer Independent of p53 Status
Javier Octavio Mejía-Hernández, Dinesh Raghu, Franco Caramia, Nicholas J. Clemons, Kenji M. Fujihara, Thomas Riseborough, Amina F.A.S. Teunisse, Aart G. Jochemsen, Lars Abrahmsén, Giovanni Blandino, Andrea Russo, Cristina Gamell, Stephen B. Fox, Catherine Mitchell, Elena A. Takano, David J. Byrne, Panimaya Jeffreena Miranda, Reem Saleh, Heather Thorne, Shahneen Sandhu, Scott Williams, Simon P. Keam, Ygal Haupt, Sue Haupt (2022). Targeting MDM4 as a Novel Therapeutic Approach in Prostate Cancer Independent of p53 Status. , 14(16), DOI: https://doi.org/10.3390/cancers14163947.
Article153 days agoTissue-resident memory T cells from a metastatic vaginal melanoma patient are tumor-responsive T cells and increase after anti-PD-1 treatment
Angela Pizzolla, Simon P. Keam, Ismael A. Vergara, Franco Caramia, Niko Thio, Minyu Wang, Nikolce Kocovski, Daniela Tantalo, Jafar S. Jabbari, George Au‐Yeung, Shahneen Sandhu, David Gyorki, Alison M. Weppler, Maurizio Perdicchio, Grant A. McArthur, Anthony T. Papenfuss, Paul J. Neeson (2022). Tissue-resident memory T cells from a metastatic vaginal melanoma patient are tumor-responsive T cells and increase after anti-PD-1 treatment. , 10(5), DOI: https://doi.org/10.1136/jitc-2022-004574.
Article153 days agoTumor immune microenvironment of primary prostate cancer with and without germline mutations in homologous recombination repair genes
Anna Trigos, Anupama Pasam, Patricia Banks, Roslyn Wallace, Christina Guo, Simon P. Keam, Heather Thorne, Catherine Mitchell, Stephen Lade, David Clouston, Alexander Hakansson, Yang Liu, Benjamin J. Blyth, Declan G. Murphy, Nathan Lawrentschuk, Damien Bolton, Daniel Moon, Phillip K. Darcy, Ygal Haupt, Scott Williams, Elena Castro, David Olmos, David L. Goode, Paul J. Neeson, Shahneen Sandhu (2022). Tumor immune microenvironment of primary prostate cancer with and without germline mutations in homologous recombination repair genes. , 10(6), DOI: https://doi.org/10.1136/jitc-2021-003744.
Article153 days ago