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The last 5 uploaded publications
Metabolic regulation of RA macrophages is distinct from RA fibroblasts and blockade of glycolysis alleviates inflammatory phenotype in both cell types
Sadiq Umar, Karol Palasiewicz, Michael V. Volin, Bianca Romay, Rani Rahat, Chandana Tetali, Shiva Arami, Mónica Gumà, Christian Ascoli, Nadera Sweiss, Ryan K. Zomorrodi, Luke O'neill, Shiva Shahrara (2021). Metabolic regulation of RA macrophages is distinct from RA fibroblasts and blockade of glycolysis alleviates inflammatory phenotype in both cell types. Cellular and Molecular Life Sciences, 78(23), pp. 7693-7707, DOI: 10.1007/s00018-021-03978-5.
Article386 days agoChronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation
Helena Shaked, Lorne J. Hofseth, Alena Chumanevich, Alexander A. Chumanevich, Jin Wang, Yinsheng Wang, Koji Taniguchi, Mónica Gumà, Steve Shenouda, Hans Clevers, Curtis C. Harris, Michael Karin (2012). Chronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation. , 109(35), DOI: https://doi.org/10.1073/pnas.1211509109.
Article41 days agoCholine uptake and metabolism modulate macrophage immunity
Elsa Sánchez‐López, Zhenyu Zhong, Alexandra Stubelius, Shannon Sweeney, Laela M. Booshehri, Laura Antonucci, Ru Liu‐Bryan, Alessia Lodi, Robert Terkeltaub, Juan Carlos Lacal, Anne N. Murphy, Hal M. Hoffman, Stefano Tiziani, Mónica Gumà, Michael Karin (2019). Choline uptake and metabolism modulate macrophage immunity. , 202(1_Supplement), DOI: https://doi.org/10.4049/jimmunol.202.supp.125.1.
Article41 days agoRIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-κB Activation
Jerry Wong, Ricard Garcia‐Carbonell, Matija Zelic, Samuel B. Ho, Brigid S. Boland, S. Yao, Shalin A. Desai, Soumita Das, Núria Planell, Philip A. Harris, Joan Font-Burgada, Koji Taniguchi, John Bertin, Azucena Salas, Manolis Pasparakis, Pete J. Gough, Michelle A. Kelliher, Michael Karin, Mónica Gumà (2019). RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-κB Activation. , 9(2), DOI: https://doi.org/10.1016/j.jcmgh.2019.10.002.
Article41 days agoCholine Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production
Elsa Sánchez‐López, Zhenyu Zhong, Alexandra Stubelius, Shannon Sweeney, Laela M. Booshehri, Laura Antonucci, Ru Liu‐Bryan, Alessia Lodi, Robert Terkeltaub, Juan Carlos Lacal, Anne N. Murphy, Hal M. Hoffman, Stefano Tiziani, Mónica Gumà, Michael Karin (2019). Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production. , 29(6), DOI: https://doi.org/10.1016/j.cmet.2019.03.011.
Article41 days ago