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The last 5 uploaded publications
HIF-1α stabilization in Phd1/3-/- mice results in increase in hematopoietic stem cell number and enhanced HSC maintenance in BM niche
Satish Khurana, Steve Stegen, Nick van Gastel, Sarah Schouteden, Peter Carmeliet, Geert Carmeliet, Catherine M. Verfaillie (2013). HIF-1α stabilization in Phd1/3-/- mice results in increase in hematopoietic stem cell number and enhanced HSC maintenance in BM niche. , 41(8), DOI: https://doi.org/10.1016/j.exphem.2013.05.142.
Article65 days agoSkeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle
Guillaume Tournaire, Shauni Loopmans, Steve Stegen, Gianmarco Rinaldi, Guy Eelen, Sophie Torrekens, Karen Moermans, Peter Carmeliet, Bart Ghesquière, Bernard Thienpont, Sarah‐Maria Fendt, Nick van Gastel, Geert Carmeliet (2022). Skeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle. , 40(4), DOI: https://doi.org/10.1016/j.celrep.2022.111105.
Article65 days agoDe novo serine synthesis regulates chondrocyte proliferation during bone development and repair
Steve Stegen, Shauni Loopmans, Ingrid Stockmans, Karen Moermans, Peter Carmeliet, Geert Carmeliet (2022). De novo serine synthesis regulates chondrocyte proliferation during bone development and repair. , 10(1), DOI: https://doi.org/10.1038/s41413-021-00185-7.
Article65 days agoThe pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes
Shauni Loopmans, Kateřina Rohlenová, Thomas Van Brussel, Ingrid Stockmans, Karen Moermans, Nicolas Peredo, Peter Carmeliet, Diether Lambrechts, Steve Stegen, Geert Carmeliet (2025). The pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes. , 7(1), DOI: https://doi.org/10.1038/s42255-024-01187-5.
Article65 days agoGlutamine Metabolism in Osteoprogenitors Is Required for Bone Mass Accrual and PTH-Induced Bone Anabolism in Male Mice
Steve Stegen, Claire-Sophie Devignes, Sophie Torrekens, Riet Van Looveren, Peter Carmeliet, Geert Carmeliet (2020). Glutamine Metabolism in Osteoprogenitors Is Required for Bone Mass Accrual and PTH-Induced Bone Anabolism in Male Mice. , 36(3), DOI: https://doi.org/10.1002/jbmr.4219.
Article65 days ago