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New Alkylated Purine Derivatives from Colletotrichum sp. F169

Abstract

An endophytic strain F169 was isolated from the plant Huperzia serrata. It was identified as Colletotrichum sp. based on the sequence at the internal transcribed spacer (ITS) region. Two new alkylated purine derivatives colletotrichadenines A (1) and B (2), as well as one known adenosine (3), were isolated from mycelia extract of the strain cultured on SDA solid medium. Their structures were elucidated by HR-ESI-MS experiment, and 1D, 2D NMR spectroscopy analysis. Colletotrichadenines A (1) and B (2) did not show obvious AChE inhibitory activity at 100 mu g/mL.

article Article

date_range 2022

language English

link Link of the paper

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Ma Ni

Lei Hong-Mei

Zhao Pei-Ji

Li Guo-Hong

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Featured Keywords

endophyte

Colletotrichum sp

F169

alkylated purine derivatives

spectroscopy analysis

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Assessment of reinforced concrete building damages following the Kahramanmaraş earthquakes in Malatya, Turkey (February 6, 2023)

Abstract

Earthquakes of magnitude Mw = 7.7 and Mw = 7.6 hit the city of Kahramanmaraş (Turkey) on 6 February 2023. These earthquakes caused serious damage in 11 provinces in Turkey resulting in over 50,000 deaths and huge economic losses with the collapse of thousands of buildings. Two consecutive devastating earthquakes have severely damaged the reinforced concrete building stock located in Malatya. There are many reasons reinforced concrete structures suffer damage under the influence of seismic loads. These reasons can be listed as material and section properties that do not comply with earthquake codes, workmanship defects, ground parameters that are not considered and design errors, as seen in field investigations after earthquakes in Turkey in the past. In this research, a field study was conducted on reinforced concrete buildings damaged after the earthquakes in Malatya province. The causes of structural damages in reinforced concrete buildings between 6–26 years of age were assessed in terms of design and material defects. The structural damages were mainly caused due to insufficient stirrups in structural members, short column, strong beam–weak column, failures of infill walls, soft story type collapse, poor concrete quality, and reinforcement corrosion. In addition to the field investigation, the spectrum relationships created using raw acceleration data obtained from DEMP (Disaster and Emergency Management Presidency) stations in Malatya province were compared with the design response spectra.

article Article

date_range 2024

language English

link Link of the paper

Collapsed buildings

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