A 6/5/5/7 heterotetracyclic indole derivative alkaloid isolated from Typhonium giganteum
Abstract
Typhoniumoid A (1), a new skeleton type alkaloid which was similar to carboline, possessed a 6/5/5/7 heterotetracyclic fused coupling with an unprecedented 7,5-spirocyclic moiety was isolated from Typhonium giganteum Engl. The structure was completely elucidated by combination of diverse methods which include one and two dimensional NMR, and ECD calculations. (C) 2019 Elsevier Ltd. All rights reserved.