Threshold-Based Overlap of Breast Cancer High-Risk Classification Using Family History, Polygenic Risk Scores, and Traditional Risk Models in 180,398 Women

Peh Joo Ho, Christine Kim Yan Loo, Roderick Y. H. Lim, Mui Heng Goh, Mustapha Abubakar, Thomas U. Ahearn, Irene L. Andrulis, Natalia Antonenkova, Kristan J. Aronson, Annelie Augustinsson, Sabine Behrens, Clara Bodelón, Natalia Bogdanova, Manjeet K. Bolla, Kristen D. Brantley, Hermann Brenner, Helen L. Byers, Nicola J. Camp, Jose E. Castelao, Melissa H. Cessna, Jenny Chang-Claude, Stephen J. Chanock, Georgia Chenevix‐Trench, Ji-Yeob Choi, Sarah V. Colonna, Kamila Czene, Mary B. Daly, Françoise Derouane, Thilo Dörk, A. Heather Eliassen, Christoph Engel, Mikael Eriksson, D. Gareth Evans, Olivia Fletcher, Lin Fritschi, Manuela Gago-Domínguez, Jeanine M. Genkinger, Willemina R.R. Geurts-Giele, Gord Glendon, Per Hall, U. Hamann, Cecilia Y. S. Ho, Weang-Kee Ho, Maartje J. Hooning, Reiner Hoppe, Anthony Howell, Keith Humphreys, Hidemi Ito, Motoki Iwasaki, Anna Jakubowska, Helena Jernström, Esther M. John, Nichola Johnson, Daehee Kang, Sung‐Won Kim, Cari M. Kitahara, Yon-Dschun Ko, Peter Kraft, Ava Kwong, Diether Lambrechts, Susanna C. Larsson, Shuai Li, Annika Lindblom, Martha Linet, Jolanta Lissowska, Artitaya Lophatananon, Robert J. MacInnis, Arto Mannermaa, Siranoush Manoukian, Sara Margolin, Keitaro Matsuo, Kyriaki Michailidou, Roger L. Milne, Nur Aishah Mohd Taib, Kenneth Muir, Rachel A. Murphy, William G. Newman, Katie M. O’Brien, Nadia Obi, Olufunmilayo I. Olopade, Mihalis I. Panayiotidis, Sue K. Park, Tjoung‐Won Park‐Simon, Alpa V Patel, Paolo Peterlongo, Dijana Plaseska‐Karanfilska, Katri Pylkäs, Muhammad Usman Rashid, Gad Rennert, Juan Rodríguez, Emmanouil Saloustros, Dale P. Sandler, Elinor J. Sawyer, Christopher G. Scott, Shamim Shahi, Xiao‐Ou Shu, Katerina Shulman, Jacques Simard, Melissa C. Southey, Jennifer Stone (2025). Threshold-Based Overlap of Breast Cancer High-Risk Classification Using Family History, Polygenic Risk Scores, and Traditional Risk Models in 180,398 Women. , 17(21), DOI: https://doi.org/10.3390/cancers17213561.