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Get Free AccessBecause of limited data, the task force could not make broad statements endorsing antidepressant use but acknowledged that individual bipolar patients may benefit from antidepressants. Regarding safety, serotonin reuptake inhibitors and bupropion may have lower rates of manic switch than tricyclic and tetracyclic antidepressants and norepinephrine-serotonin reuptake inhibitors. The frequency and severity of antidepressant-associated mood elevations appear to be greater in bipolar I than bipolar II disorder. Hence, in bipolar I patients antidepressants should be prescribed only as an adjunct to mood-stabilizing medications.
Isabella Pacchiarotti, David J. Bond, Ross J. Baldessarini, Willem A. Nolen, Heinz Grunze, Rasmus Wentzer Licht, Robert M. Post, Michael Berk, Guy M. Goodwin, Gary S. Sachs, Leonardo Tondo, Robert L. Findling, Eric A. Youngstrom, Mauricio Tohen, Juan Undurraga, Ana González‐Pinto, Joseph F. Goldberg, Ayşegül Yıldız, Lori L. Altshuler, Joseph R. Calabrese, Philip B. Mitchell, Michael E. Thase, Athanasios Koukopoulos, Francesc Colom, Mark A. Frye, Gin S. Malhi, Konstantinos Ν. Fountoulakis, Gustavo Vázquez, Roy H. Perlis, Terence A. Ketter, Frederick Cassidy, Hagop S. Akiskal, Jean-Michel Azorin, Marc Valentí, Diego Hidalgo‐Mazzei, Beny Lafer, Tadafumi Kato, Lorenzo Mazzarini, Anabel Martínez‐Arán, Gordon Parker, Daniel Souery, Ayşegül Özerdem, Susan L. McElroy, Paolo Girardi, Michael Bauer, Lakshmi N. Yatham, Carlos A. Zarate, Andrew A. Nierenberg, Boris Birmaher, Shigenobu Kanba, Rif S. El‐Mallakh, Alessandro Serretti, Zoltán Rihmer, Allan H. Young, Georgios D. Kotzalidis, Glenda MacQueen, Charles L. Bowden, S. Nassir Ghaemi, Carlos López‐Jaramillo, Janusz Rybakowski, Kyooseob Ha, Giulio Perugi, Siegfried Kasper, Jay D. Amsterdam, Robert M. A. Hirschfeld, Flávio Kapczinski, Eduard Vieta (2013). The International Society for Bipolar Disorders (ISBD) Task Force Report on Antidepressant Use in Bipolar Disorders. , 170(11), DOI: https://doi.org/10.1176/appi.ajp.2013.13020185.
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Type
Article
Year
2013
Authors
67
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1176/appi.ajp.2013.13020185
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