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  5. The association between biological rhythms, depression, and functioning in bipolar disorder: a large multi‐center study

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Article
en
2015

The association between biological rhythms, depression, and functioning in bipolar disorder: a large multi‐center study

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en
2015
Vol 133 (2)
Vol. 133
DOI: 10.1111/acps.12442

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Eduard Vieta
Eduard Vieta

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Michele Pinho
Manpreet Sehmbi
Lauren E. Cudney
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Abstract

Our study shows a dose-dependent association between the severity of depressive symptoms and degree of biological rhythms disturbance. Biological rhythms disturbance was also an independent predictor of functional impairment. Although the directionality of this relationship remains unknown, our results suggest that stability of biological rhythms should be an important target of acute and long-term management of bipolar disorder and may aid in the improvement of functioning.

How to cite this publication

Michele Pinho, Manpreet Sehmbi, Lauren E. Cudney, Márcia Kauer-Sant’Anna, Pedro Vieira da Silva Magalhães, María Reinares, Caterina del Mar Bonnín, Roberto B. Sassi, Flávio Kapczinski, Francesc Colom, Eduard Vieta, Benício N. Frey, Adriane Ribeiro Rosa (2015). The association between biological rhythms, depression, and functioning in bipolar disorder: a large multi‐center study. , 133(2), DOI: https://doi.org/10.1111/acps.12442.

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Publication Details

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Article

Year

2015

Authors

13

Datasets

0

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0

Language

en

DOI

https://doi.org/10.1111/acps.12442

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