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Get Free AccessIn article number 2001750, Kui Zhu, Ben Zhong Tang and co‐workers demonstrate that aggregationinduced emission luminogens such as TBPs trigger ROS‐mediated membrane damage to effectively kill internalized bacteria without resistance development. Intriguingly, TBPs promote mitochondria dependent autophagy to eliminate such bacteria in host cells. Similar to vancomycin, TBPs demonstrate high efficacy against notorious bacterial infections in vivo. [Image: see text]
Ying Li, Fei Liu, Jiangjiang Zhang, Xiaoye Liu, Peihong Xiao, Haotian Bai, Shang Chen, Dong Wang, Simon H. P. Sung, Ryan T. K. Kwok, Jianzhong Shen, Kui Zhu, Ben Zhong Tang (2021). Targeting Multidrug‐Resistant Bacteria: Efficient Killing of Multidrug‐Resistant Internalized Bacteria by AIEgens In Vivo (Adv. Sci. 9/2021). , 8(9), DOI: https://doi.org/10.1002/advs.202170051.
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Type
Article
Year
2021
Authors
13
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1002/advs.202170051
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