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Get Free AccessSupplementary Figure 1: Electrophoretic mobility shift assays (EMSA) for CCNE1 SNPs rs8102137 and rs7257330. Supplementary Figure 2: Alignment of cyclin E protein isoforms - WT1, WT2 and ES and ET. Supplementary Figure 3: Functional analysis of cyclin E isoforms.Supplementary Table 1: Description of sub-studies included in NCI-GWAS1 and GWAS2 of bladder cancer. Supplementary Table 2: Characteristics of bladder tissue samples used for mRNA expression analysis. Supplementary Table 3: PCR primers, genotyping and gene expression assays, EMSA probes and antibodies. Supplementary Table 4: Bladder cancer stage and grade information for patients in the combined GWAS1+2 set. Supplementary Table 6: Association with bladder cancer risk with mutual adjustment for CCNE1 variants. Supplementary Table 7: Association with bladder cancer risk for CCNE1 variants previously associated with other cancers and for two non-synonymous coding variants. Supplementary Table 8: Association between cyclin E protein expression (IHC scores), bladder cancer patient characteristics and CCNE1 variants.
Yi‐Ping Fu, Indu Kohaar, Lee E. Moore, Petra H. Lenz, Jonine D. Figueroa, Wei Tang, Patricia Porter‐Gill, Nilanjan Chatterjee, Alexandra Scott-Johnson, Montserrat García‐Closas, Brian Muchmore, Dalsu Baris, Ashley Paquin, Kris Ylaya, Molly Schwenn, Andrea B. Apolo, Margaret R. Karagas, McAnthony Tarway, Alison Johnson, Adam Mumy, Alan R. Schned, Liliana Guédez, Michael A. Jones, Masatoshi Kida, GM Monawar Hosain, Núria Malats, Adonina Tardón, Cònsol Serra, Alfredo Carrato, Reina García‐Closas, Josep Lloreta, Xifeng Wu, Mark P. Purdue, Gerald L. Andriole, Robert L. Grubb, Amanda Black, Maria Teresa Landi, Neil E. Caporaso, Paolo Vineis, Afshan Siddiq, H. Bas Bueno‐de‐Mesquita, Dimitrios Trichopoulos, Börje Ljungberg, Gianluca Severi, Elisabete Weiderpass, Vittorio Krogh, Miren Dorronsoro, Ruth C. Travis, Anne Tjønneland, Paul Brennan, Jenny Chang‐Claude, Elio Riboli, Jennifer Prescott, Constance Chen, Immaculata De Vivo, Edward Govannucci, David J. Hunter, Peter Kraft, Sara Lindstrӧm, Susan M. Gapstur, Eric J. Jacobs, W. Ryan Diver, Demetrius Albanes, Stephanie J. Weinstein, Jarmo Virtamo, Charles Kooperberg, Chancellor Hohensee, Rebecca J. Rodabough, Victoria K. Cortessis, David V. Conti, Manuela Gago-Domínguez, Mariana C. Stern, Malcolm C. Pike, David Van Den Berg, Jian‐Min Yuan, Christopher A. Haiman, Olivier Cussenot, Géraldine Cancel‐Tassin, Morgan Rouprêt, Éva Compérat, Stefano Porru, Angela Carta, Sofia Pavanello, Cecilia Arici, Giuseppe Mastrangelo, H. Barton Grossman, Zhaoming Wang, Xiang Deng, Charles C. Chung, Amy Hutchinson, Laurie Burdette, William Wheeler, Joseph F. Fraumeni, Stephen J. Chanock, Stephen M. Hewitt, Debra T. Silverman, Nathaniel Rothman, Ludmila Prokunina‐Olsson (2023). Supplementary Materials, Figures 1 - 3, Tables 1 - 4, 6 - 8 from The 19q12 Bladder Cancer GWAS Signal: Association with Cyclin E Function and Aggressive Disease. , DOI: https://doi.org/10.1158/0008-5472.22403567.
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Type
Preprint
Year
2023
Authors
98
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1158/0008-5472.22403567
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