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Get Free AccessMRI of the brain allows to demonstrate and quantify increasing disruption of structural connectivity involving the sensorimotor networks in ALS, mirroring disease stages. Frontotemporal functional disconnection seems to characterize only advanced disease phases. Our findings support the utility of MRI connectomics to stratify patients and stage brain pathology in ALS in a reproducible way, which may mirror clinical progression.
Edoardo Gioele Spinelli, Alma Ghirelli, Silvia Basaia, Elisa Canu, Veronica Castelnovo, Camilla Cividini, Tommaso Russo, Paride Schito, Yuri Falzone, Nilo Riva, Massimo Filippi, Federica Agosta (2023). Structural and Functional Brain Network Connectivity at Different King's Stages in Patients With Amyotrophic Lateral Sclerosis. , 102(2), DOI: https://doi.org/10.1212/wnl.0000000000207946.
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Type
Article
Year
2023
Authors
12
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1212/wnl.0000000000207946
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