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Get Free AccessThis multicenter study showed widespread motor and extramotor network degeneration in ALS and PLS, suggesting that graph analysis and connectomics might represent a powerful approach to detect upper motor neuron degeneration, extramotor brain changes, and network reorganization associated with the disease. Network-based advanced MRI provides an objective in vivo assessment of motor neuron diseases, delivering potential prognostic markers.
Silvia Basaia, Federica Agosta, Camilla Cividini, Francesca Trojsi, Nilo Riva, Edoardo Gioele Spinelli, Cristina Moglia, Cinzia Femiano, Veronica Castelnovo, Elisa Canu, Yuri Falzone, Maria Rosaria Monsurrò, Andrea Falini, Adriano Chiò, Gioacchino Tedeschi, Massimo Filippi (2020). Structural and functional brain connectome in motor neuron diseases. , 95(18), DOI: https://doi.org/10.1212/wnl.0000000000010731.
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Type
Article
Year
2020
Authors
16
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1212/wnl.0000000000010731
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