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  5. Patterns of subregional cerebellar atrophy across epilepsy syndromes: An ENIGMA‐Epilepsy study

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Article
en
2024

Patterns of subregional cerebellar atrophy across epilepsy syndromes: An ENIGMA‐Epilepsy study

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0 Files

en
2024
Vol 65 (4)
Vol. 65
DOI: 10.1111/epi.17881

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Dan Joseph Stein
Dan Joseph Stein

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Rebecca Kerestes
Andrew Perry
Lucy Vivash
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Abstract

We provide robust evidence of deep cerebellar and posterior lobe subregional gray matter volume loss in patients with chronic epilepsy. Volume loss was maximal for posterior subregions implicated in nonmotor functions, relative to motor regions of both the anterior and posterior lobe. Associations between cerebral and cerebellar changes, and variability of neuroanatomical profiles across epilepsy syndromes argue for more precise incorporation of cerebellar subregional damage into neurobiological models of epilepsy.

How to cite this publication

Rebecca Kerestes, Andrew Perry, Lucy Vivash, Terence J. O’Brien, Marina K. M. Alvim, Donatello Arienzo, Ítalo Karmann Aventurato, B. Alice, Gabriel Ferri Baltazar, Núria Bargalló, Benjamin Bender, Ricardo Brioschi, Eva Bürkle, Maria Eugenia Caligiuri, Fernando Cendes, Jane de Tisi, John S. Duncan, Jerome Engel, Sonya Foley, Francesco Fortunato, Antonio Gambardella, Thea Giacomini, Renzo Guerrini, Gerard Hall, Khalid Hamandi, Victoria Ives‐Deliperi, Rafael Batista João, Simon S. Keller, Benedict Kleiser, Angelo Labate, Matteo Lenge, Cassandra Marotta, Pascal Martin, Mario Mascalchi, Stefano Meletti, Conor Owens‐Walton, Costanza Parodi, Saül Pascual‐Diaz, David Powell, Jun Rao, Michael Rebsamen, Johannes Reiter, Antonella Riva, Theodor Rüber, Christian Rummel, Freda Scheffler, Mariasavina Severino, Lucas Scárdua Silva, Richard J. Staba, Dan Joseph Stein, Pasquale Striano, Peter N. Taylor, Sophia I. Thomopoulos, Paul M. Thompson, Domenico Tortora, Anna Elisabetta Vaudano, Bernd Weber, Roland Wiest, Gavin P. Winston, Clarissa Lin Yasuda, Hong Zheng, Carrie R. McDonald, Sanjay M. Sisodiya, Ian H. Harding (2024). Patterns of subregional cerebellar atrophy across epilepsy syndromes: An ENIGMA‐Epilepsy study. , 65(4), DOI: https://doi.org/10.1111/epi.17881.

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Publication Details

Type

Article

Year

2024

Authors

64

Datasets

0

Total Files

0

Language

en

DOI

https://doi.org/10.1111/epi.17881

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