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Get Free AccessEvidence supporting the routine, nonselective use of NGS in patients with sarcoma is currently limited. Given the complexity, the decision to perform an NGS panel, as well as the interpretation and use of its results for diagnostic or therapeutic purposes, should take place only in sarcoma-expert institutions, including a multidisciplinary review. The results of multigene panels performed in nonexpert sarcoma centers cannot replace the pathology review or the recommendation of NGS-guided therapies without prior evaluation by sarcoma experts.
César Serrano, Sebastian Bauer, Jean Yves Blay, Paolo G. Casali, Carlo María Cicala, Angelo Paolo Dei Tos, Antonia Digklia, Hans Gelderblom, Antoine Italiano, Robin L. Jones, Bernd Kasper, Anastasios Kyriazoglou, François Le Loarer, Javier Martín‐Broto, Andrea Napolitano, Piotr Rutkowski, Silvia Stacchiotti, William D. Tap, David J. Thomas, Khin Thway, Claudia Valverde, Winette T.A. van der Graaf, Eva Wardelmann, Judith V.M.G. Bovée (2025). Guidelines for Next-Generation Sequencing in Sarcoma Diagnosis and Treatment. , 11(12), DOI: https://doi.org/10.1001/jamaoncol.2025.3608.
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Type
Article
Year
2025
Authors
24
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1001/jamaoncol.2025.3608
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