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Get Free AccessThe results of this cohort study suggest that graded kidney response criteria offers clinically and prognostically meaningful information for treating patients with kidney AL amyloidosis. The response criteria potentially inform kidney survival based on the depth of reduction in 24-hour proteinuria levels and demonstrate an OS advantage for those able to achieve kidCR/kidVGPR compared with kidPR/kidNR. Taken together, achievement of at least kidVGPR by 12 months is needed to ultimately improve kidney and patient survival.
Eli Muchtar, Brendan Wisniowski, Susan Geyer, Giovanni Palladini, Paolo Milani, Giampaolo Merlini, Stefan Schönland, Kaya Veelken, Ute Hegenbart, Nelson Leung, Angela Dispenzieri, Shaji Kumar, Efstathios Kastritis, Meletios A Dimopoulos, Michaela Liedtke, Patricia Ulloa, Vaishali Sanchorawala, Raphaël Szalat, Katharine Dooley, Heather Landau, Erica Petrlik, Suzanne Lentzsch, Alexander Coltoff, Joan Bladé, María Teresa Cibeira, Oliver C. Cohen, Darren Foard, Jullian Gillmore, Helen J. Lachmann, Ashutosh Wechalekar, Morie A. Gertz (2024). Graded Organ Response and Progression Criteria for Kidney Immunoglobulin Light Chain Amyloidosis. , 10(10), DOI: https://doi.org/10.1001/jamaoncol.2024.2629.
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Type
Article
Year
2024
Authors
31
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1001/jamaoncol.2024.2629
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