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  5. DNA Translocation in Inorganic Nanotubes

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Article
en
2005

DNA Translocation in Inorganic Nanotubes

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en
2005
Vol 5 (9)
Vol. 5
DOI: 10.1021/nl0509677

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Peidong Yang
Peidong Yang

University of California, Berkeley

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Rong Fan
Rohit Karnik
Min Yue
+3 more

Abstract

Inorganic nanotubes were successfully integrated with microfluidic systems to create nanofluidic devices for single DNA molecule sensing. Inorganic nanotubes are unique in their high aspect ratio and exhibit translocation characteristics in which the DNA is fully stretched. Transient changes of ionic current indicate DNA translocation events. A transition from current decrease to current enhancement during translocation was observed on changing the buffer concentration, suggesting interplay between electrostatic charge and geometric blockage effects. These inorganic nanotube nanofluidic devices represent a new platform for the study of single biomolecule translocation with the potential for integration into nanofluidic circuits.

How to cite this publication

Rong Fan, Rohit Karnik, Min Yue, Deyu Li, Arun Majumdar, Peidong Yang (2005). DNA Translocation in Inorganic Nanotubes. , 5(9), DOI: https://doi.org/10.1021/nl0509677.

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Publication Details

Type

Article

Year

2005

Authors

6

Datasets

0

Total Files

0

Language

en

DOI

https://doi.org/10.1021/nl0509677

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