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  5. Diagnosis of bipolar disorders and body mass index predict clustering based on similarities in cortical thickness—ENIGMA study in 2436 individuals

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Article
en
2021

Diagnosis of bipolar disorders and body mass index predict clustering based on similarities in cortical thickness—ENIGMA study in 2436 individuals

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en
2021
Vol 24 (5)
Vol. 24
DOI: 10.1111/bdi.13172

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Eduard Vieta
Eduard Vieta

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Sean R. McWhinney
Christoph Abé
Martin Alda
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Abstract

We provide evidence that both BD and obesity are associated with similar alterations in cortical thickness, but not surface area. The fact that obesity increased the chance of having low cortical thickness could explain differences in cortical measures among people with BD. The thinner cortex in individuals with higher BMI, which was additive and similar to the BD-associated alterations, may suggest that treating obesity could lower the extent of cortical thinning in BD.

How to cite this publication

Sean R. McWhinney, Christoph Abé, Martin Alda, Francesco Benedetti, Erlend Bøen, Caterina del Mar Bonnín, Tiana Borgers, Katharina Brosch, Erick J. Canales‐Rodríguez, Dara M. Cannon, Udo Dannlowski, Ana M. Díaz‐Zuluaga, Lorielle M. F. Dietze, Torbjørn Elvsåshagen, Lisa T. Eyler, Janice M. Fullerton, José Manuel Goikolea, Janik Goltermann, Dominik Grotegerd, Bartholomeus C. M. Haarman, Tim Hahn, Fleur M. Howells, Martin Ingvar, Tilo Kircher, Axel Krug, Rayus Kuplicki, Mikael Landén, Hannah Lemke, Benny Liberg, Carlos López‐Jaramillo, Ulrik Fredrik Malt, Fiona M. Martyn, Elena Mazza, Colm McDonald, Genevieve McPhilemy, Sandra Meier, Susanne Meinert, Tina Meller, Elisa Melloni, Philip B. Mitchell, Leila Nabulsi, Igor Nenadić, Nils Opel, Roel A. Ophoff, Bronwyn J. Overs, Julia‐Katharina Pfarr, Julian A. Pineda‐Zapata, Edith Pomarol‐Clotet, Joaquim Raduà, Jonathan Repple, Maike Richter, Kai G. Ringwald, Gloria Roberts, Alex J. Ross, Raymond Salvador, Jonathan Savitz, Simon Schmitt, Peter R. Schofield, Kang Sim, Dan Joseph Stein, Frederike Stein, Henk Temmingh, Katharina Thiel, Sophia I. Thomopoulos, Neeltje E.M. van Haren, Holly Van Gestel, Cristian Vargas, Eduard Vieta, Annabel Vreeker, Lena Waltemate, Lakshmi N. Yatham, Christopher R. K. Ching, Ole A. Andreassen, Paul M. Thompson, Tomáš Hájek (2021). Diagnosis of bipolar disorders and body mass index predict clustering based on similarities in cortical thickness—ENIGMA study in 2436 individuals. , 24(5), DOI: https://doi.org/10.1111/bdi.13172.

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Publication Details

Type

Article

Year

2021

Authors

75

Datasets

0

Total Files

0

Language

en

DOI

https://doi.org/10.1111/bdi.13172

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