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Get Free AccessAbstract We present several deep learning models for assessing the morphometric fidelity of deep grey matter region models extracted from brain MRI. We test three different convolutional neural net architectures (VGGNet, ResNet and Inception) over 2D maps of geometric features. Further, we present a novel geometry feature augmentation technique based on parametric spherical mapping. Finally, we present an approach for model decision visualization, allowing human raters to see the areas of subcortical shapes most likely to be deemed of failing quality by the machine. Our training data is comprised of 5200 subjects from the ENIGMA Schizophrenia MRI cohorts, and our test dataset contains 1500 subjects from the ENIGMA Major Depressive Disorder cohorts. Our final models reduce human rater time by 46-70%. ResNet outperforms VGGNet and Inception for all of our predictive tasks.
Dmitry Petrov, Boris A. Gutman, Е.Е. Кузнецов, Theo G.M. van Erp, Jessica A. Turner, Lianne Schmaal, Dick J. Veltman, Lei Wang, Kathryn Alpert, Dmitry Isaev, Artemis Zavaliangos‐Petropulu, Christopher R. K. Ching, Vince D. Calhoun, David C. Glahn, Theodore D. Satterthwaite, Ole A. Andreassen, Stefan Borgwardt, Fleur M. Howells, Nynke A. Groenewold, Aristotle N. Voineskos, Joaquim Raduà, Steven G. Potkin, Benedicto Crespo‐Facorro, Diana Tordesillas-Gutirrez, Li Shen, И. С. Лебедева, Gianfranco Spalletta, Gary Donohoe, Peter Kochunov, Pedro G. P. Rosa, Anthony James, Udo Dannlowski, Bernhard T. Baune, A. Aleman, Ian H. Gotlib, Henrik Walter, Martin Walter, Jair C. Soares, Stefan Ehrlich, Ruben C. Gur, N. Trung Doan, Ingrid Agartz, Lars T. Westlye, Fabienne Harrisberger, Anita Riecher‐Rössler, Anne Uhlmann, Dan Joseph Stein, Erin W. Dickie, Edith Pomarol‐Clotet, Paola Fuentes‐Claramonte, Erick J. Canales‐Rodríguez, Raymond Salvador, Alexander J. Huang, Roberto Roiz-Santiaez, Shan Cong, A. S. Tomyshev, Fabrizio Piras, Daniela Vecchio, Nerisa Banaj, Valentina Ciullo, Elliot Hong, Geraldo F. Busatto, Marcus V. Zanetti, Maurício H. Serpa, Simon Červenka, Sinéad Kelly, Dominik Grotegerd, Matthew D. Sacchet, Ilya M. Veer, Meng Li, Mon-Ju Wu, Benson Irungu, Esther Walton, Paul M. Thompson (2018). Deep Learning for Quality Control of Subcortical Brain 3D Shape Models. , DOI: https://doi.org/10.1101/402255.
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Type
Preprint
Year
2018
Authors
74
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1101/402255
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