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Get Free AccessThis study identified structural changes associated with illness severity, OC symptom dimensionality, and comorbidities. Our results emphasize the role of the OFC and insula in OCD and suggest comorbidity-specific alterations. The absence of case-control differences may stem from the inclusion of medication-free individuals and clinical heterogeneity within the OCD group.
Niels T. de Joode, Chris Vriend, Petra J. W. Pouwels, Feng Liu, Maria Concepción García Otaduy, Bruno Pastorello, Frances Robertson, Jonathan Ipser, Seonjoo Lee, Anton J.L.M. van Balkom, Dianne M. Hezel, Marcelo C. Batistuzzo, Marcelo Q. Hoexter, Sheshachala Karthik, Janardhanan C. Narayanaswamy, Ganesan Venkatasubramanian, Christine Löchner, Eurı́pedes Constantino Miguel, Y.C. Janardhan Reddy, Roseli Gedanke Shavitt, Dan Joseph Stein, Melanie M. Wall, Blair Simpson, Odile A. van den Heuvel (2025). Cortical and subcortical structural alterations in obsessive-compulsive disorder: relationships between morphology and clinical profiles in the Global OCD study. , DOI: https://doi.org/10.1101/2025.07.23.25332068.
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Type
Preprint
Year
2025
Authors
24
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1101/2025.07.23.25332068
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